Technology Process of C18H18O8
There total 5 articles about C18H18O8 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium on activated charcoal; hydrogen;
In
tetrahydrofuran; methanol; dichloromethane;
at 20 ℃;
for 24h;
DOI:10.1002/cbic.201100044
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / N,N-dimethyl-formamide / 48 h / 20 °C
2: sodium hydride / N,N-dimethyl-formamide / 6 h / 0 °C
3: trichlorophosphate / 19 h / 20 - 75 °C
4: sodium hydride / N,N-dimethyl-formamide / 24 h / 20 °C
5: palladium on activated charcoal; hydrogen / tetrahydrofuran; methanol; dichloromethane / 24 h / 20 °C
With
palladium on activated charcoal; hydrogen; sodium hydride; potassium carbonate; trichlorophosphate;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
3: Vilsmeier-Haack reaction / 4: Horner-Wadsworth-Emmons olefination;
DOI:10.1002/cbic.201100044
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / N,N-dimethyl-formamide / 6 h / 0 °C
2: trichlorophosphate / 19 h / 20 - 75 °C
3: sodium hydride / N,N-dimethyl-formamide / 24 h / 20 °C
4: palladium on activated charcoal; hydrogen / tetrahydrofuran; methanol; dichloromethane / 24 h / 20 °C
With
palladium on activated charcoal; hydrogen; sodium hydride; trichlorophosphate;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
2: Vilsmeier-Haack reaction / 3: Horner-Wadsworth-Emmons olefination;
DOI:10.1002/cbic.201100044
