2-hydroxy-3-n-propoxybenzaldehyde

Base Information

• Chemical Name: 2-hydroxy-3-n-propoxybenzaldehyde
• CAS No.: 222031-84-7
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.203
• Mol file: 222031-84-7.mol

Synonyms:2-hydroxy-3-n-propoxybenzaldehyde

Chemical Property of 2-hydroxy-3-n-propoxybenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-hydroxy-3-n-propoxybenzaldehyde

There total 3 articles about 2-hydroxy-3-n-propoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.2%

2,3-dihydroxybenzaldehyde (24677-78-9) + propyl bromide (106-94-5) → 2-hydroxy-3-n-propoxybenzaldehyde (222031-84-7)

Guidance literature:

2,3-dihydroxybenzaldehyde; With sodium hydride; In dimethyl sulfoxide; mineral oil; for 1h; Inert atmosphere;

propyl bromide; In dimethyl sulfoxide; mineral oil; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.ejmech.2015.01.054

Reference yield:

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 2-hydroxy-3-n-propoxybenzaldehyde (222031-84-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous NaOH

2: in ein zuvor auf 170grad erhitztes Gemisch von Glycerin und Borsaeure bei 150-155grad und Erwaermen des abgekuehlten Reaktionsgemisches mit wss.H₂SO₄

With sodium hydroxide;

Reference yield:

hexamethylenetetramine (100-97-0) + 2-propoxyphenol (6280-96-2) → 2-hydroxy-3-n-propoxybenzaldehyde (222031-84-7)

Guidance literature:

in ein zuvor auf 170grad erhitztes Gemisch von Glycerin und Borsaeure bei 150-155grad und Erwaermen des abgekuehlten Reaktionsgemisches mit wss.H₂SO₄;

upstream raw materials:

hexamethylenetetramine

2-propoxyphenol

benzene-1,2-diol

2,3-dihydroxybenzaldehyde

Refernces