Cyclohexyl phenyl ketone

Base Information

• Chemical Name: Cyclohexyl phenyl ketone
• CAS No.: 116204-80-9
• Molecular Formula: C₁₃H₁₆O
• Molecular Weight: 189.258
• Mol file: 116204-80-9.mol

Synonyms:Cyclohexyl phenyl ketone

Chemical Property of Cyclohexyl phenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of Cyclohexyl phenyl ketone

There total 4 articles about Cyclohexyl phenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Phenylcyclohexylmethanol → Cyclohexyl phenyl ketone (116204-80-9)

Guidance literature:

With pyridinium chlorochromate;

DOI:10.1016/0040-4039(96)01117-3

Reference yield:

(13)C-benzaldehyde (10383-90-1) + cyclohexane (110-82-7,25012-93-5) → cyclohexylcyclohexane (92-51-3) + 1,2-13C-benzoin (53290-42-9) + Benzylcyclohexane + Cyclohexyl phenyl ketone (116204-80-9) + Phenylcyclohexylmethanol + 1-Cyclohexyl-1,2-diphenylethanol

Guidance literature:

Product distribution; Irradiation;

DOI:10.1021/jo00084a030

Reference yield:

(13)C-benzaldehyde (10383-90-1) → Cyclohexyl phenyl ketone (116204-80-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / diethyl ether / -40 °C

2: 91 percent / PCC

With pyridinium chlorochromate; In diethyl ether;

DOI:10.1016/0040-4039(96)01117-3

upstream raw materials:

⁽¹³⁾C-benzaldehyde

cyclohexane

[α-13C]-benzyl alcohol

Downstream raw materials:

C₁₃⁽¹³⁾CH₁₆Cl₂

C₁₃⁽¹³⁾CH₁₆Br₂

Refernces

• 1、 Xiang, Jason S.,Fuchs. "Mechanistic aspects of the C-H alkynylation reaction of acetylenic triflones. Determination of phenyl versus cyclohexyl migratory aptitude for a vinylidine carbene". . p. 5269 - 5272. Retrieved 2007/10/03.