Technology Process of (4-(ethoxycarbonyl)phenyl)zinc pivalate
There total 3 articles about (4-(ethoxycarbonyl)phenyl)zinc pivalate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-iodobenzoic acid ethyl ester;
With
TurboGrignard;
In
tetrahydrofuran;
at -30 ℃;
for 0.5h;
Inert atmosphere;
Schlenk technique;
zinc trimethylacetate;
In
tetrahydrofuran;
at -30 - 25 ℃;
for 0.25h;
Inert atmosphere;
Schlenk technique;
DOI:10.1002/chem.201403015
- Guidance literature:
-
With
TurboGrignard;
In
tetrahydrofuran;
at 30 ℃;
for 0.5h;
Product distribution / selectivity;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrahydrofuran / 1.5 h / 0 - 25 °C / Inert atmosphere
2.1: TurboGrignard / tetrahydrofuran / 0.5 h / -30 °C / Inert atmosphere; Schlenk technique
2.2: 0.25 h / -30 - 25 °C / Inert atmosphere; Schlenk technique
With
TurboGrignard;
In
tetrahydrofuran;
DOI:10.1002/chem.201403015
