Prosta-5,13-dien-1-oic acid,9,11,15-trihydroxy-15-methyl-,methyl ester,(5Z,9R,11R,13E,15S)-

Base Information

• Chemical Name: Prosta-5,13-dien-1-oic acid,9,11,15-trihydroxy-15-methyl-,methyl ester,(5Z,9R,11R,13E,15S)-
• CAS No.: 62776-96-9
• Molecular Formula: C22H38O5
• Molecular Weight: 382.53400
• Mol file: 62776-96-9.mol

Synonyms:Carboprost methylate;

Chemical Property of Prosta-5,13-dien-1-oic acid,9,11,15-trihydroxy-15-methyl-,methyl ester,(5Z,9R,11R,13E,15S)-

Chemical Property:

• Boiling Point: 501.7±50.0 °C(Predicted)
• PKA: 14.66±0.29(Predicted)
• PSA: 86.99000
• Density: 1.096±0.06 g/cm3(Predicted)
• LogP: 3.52140

Purity/Quality:

98%,99%, ^*data from raw suppliers

Carboprost Methylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Prosta-5,13-dien-1-oic acid,9,11,15-trihydroxy-15-methyl-,methyl ester,(5Z,9R,11R,13E,15S)-

There total 7 articles about Prosta-5,13-dien-1-oic acid,9,11,15-trihydroxy-15-methyl-,methyl ester,(5Z,9R,11R,13E,15S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 15-methyl-8β,9α,12α-prostaglandin-F2-methylester (35700-21-1,35700-22-2,53275-61-9,53275-62-0,53275-64-2,53275-66-4,53275-67-5,53275-68-6,54142-09-5,54142-10-8,54142-20-0,54142-25-5,62446-62-2,62446-64-4,62776-96-9,80124-59-0,88644-12-6,90695-60-6,90695-61-7,96744-82-0,100019-31-6,113626-86-1)

Guidance literature:

15-methyl-8β,12α,15β-PGE2-methylester, 1) Na-borohydride, methanol, 2) acetic acid;

Reference yield:

→ (Z)-7-[(1R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hydroxy-3-methyl-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid methyl ester (35700-21-1,35700-22-2,53275-61-9,53275-62-0,53275-64-2,53275-66-4,53275-67-5,53275-68-6,54142-09-5,54142-10-8,54142-20-0,54142-25-5,62446-62-2,62446-64-4,62776-96-9,80124-59-0,88644-12-6,90695-60-6,90695-61-7,96744-82-0,100019-31-6,113626-86-1)

Guidance literature:

Entspr. 15-(R,S)-Saeure, CH2N2;

Reference yield:

→ 15-methyl-8β,9β,12α-prostaglandin-F2-methylester (35700-21-1,35700-22-2,53275-61-9,53275-62-0,53275-64-2,53275-66-4,53275-67-5,53275-68-6,54142-09-5,54142-10-8,54142-20-0,54142-25-5,62446-62-2,62446-64-4,62776-96-9,80124-59-0,88644-12-6,90695-60-6,90695-61-7,96744-82-0,100019-31-6,113626-86-1)

Guidance literature:

15-methyl-8β,12α-PGE2-methylester (LI), 1) Na-borohydride, methanol, 2) acetic acid;

Refernces