1alpha,24-Dihydroxycholecalciferol

Base Information

• Chemical Name: 1alpha,24-Dihydroxycholecalciferol
• CAS No.: 60965-80-2
• Deprecated CAS: 124816-12-2
• Molecular Formula: C₂₇H₄₄O₃
• Molecular Weight: 416.645
• Mol file: 60965-80-2.mol

Synonyms:1 alpha,24-dihydroxycholecalciferol;1 alpha,24-dihydroxyvitamin D3;1 alpha,24-dihydroxyvitamin D3, (1alpha,3beta,5Z,7E,24R)-isomer;1 alpha,24-dihydroxyvitamin D3, (1alpha,3beta,5Z,7E,24S)-isomer;1,24-dihydroxycholecalciferol;1,24-dihydroxyvitamin D3;Curatoderm;PRI-2191;Tacalcitol

Chemical Property of 1alpha,24-Dihydroxycholecalciferol

Chemical Property:

• Vapor Pressure: 4.05E-15mmHg at 25°C
• Boiling Point: 565°C at 760 mmHg
• Flash Point: 238.4°C
• PSA: 60.69000
• Density: 1.06g/cm³
• LogP: 5.56060
• XLogP3: 5.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 416.32904526
• Heavy Atom Count: 30
• Complexity: 676

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C(CCC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C)O
• Isomeric SMILES: C[C@H](CCC(C(C)C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C

Technology Process of 1alpha,24-Dihydroxycholecalciferol

There total 4 articles about 1alpha,24-Dihydroxycholecalciferol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1α,24χ-Dihydroxycholecalciferol (57333-95-6,57333-96-7,60965-80-2,61616-90-8,142864-53-7)

Guidance literature:

1α,3β,24-Trihydroxycholesta-5,7-dien, Bestrahlung;

Reference yield:

1α-hydroxy-3β,24-dibenzoyloxycholesta-5,7-diene (60934-49-8) → 9,10-secocholesta-5,7,10(19)-triene-1α,3β,24-triol (60965-80-2) + 1α-hydroxy-24-benzoyloxycholecalciferol-3β-benzoate

Guidance literature:

In diethyl ether;

Reference yield:

→ 9,10-secocholesta-5,7,10(19)-triene-1α,3β,24-triol (60965-80-2)

Guidance literature:

upstream raw materials:

1α-hydroxy-3β,24-dibenzoyloxycholesta-5,7-diene

Refernces

• 1、 -. "Novel 1α,24-dihydroxycholecalciferol compositions, novel precursors thereof, and processes for preparing them". . . Retrieved 2008/06/13.