inosine 5'-(tetrahydrogen triphosphate)

Base Information

• Chemical Name: inosine 5'-(tetrahydrogen triphosphate)
• CAS No.: 132-06-9
• Molecular Formula: C10H15N4O14P3
• Molecular Weight: 508.169
• Mol file: 132-06-9.mol

Synonyms:5'-ITP;ITP;Inosine 5'-triphosphate;Inosine triphosphate;

Chemical Property of inosine 5'-(tetrahydrogen triphosphate)

Chemical Property:

• Boiling Point: 994.9 °C at 760 mmHg
• PKA: pK3:2.2(－2);pK4:6.92(－3);pk5:7.68(-4) (25°C)
• Flash Point: 555.5 °C
• PSA: 302.77000
• Density: 2.63 g/cm³
• LogP: -1.50560

Purity/Quality:

99%, ^*data from raw suppliers

ITP 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of inosine 5'-(tetrahydrogen triphosphate)

There total 4 articles about inosine 5'-(tetrahydrogen triphosphate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Inosine (58-63-9) → Inosine 5'-triphosphate (132-06-9)

Guidance literature:

Inosine; With trimethyl phosphite; trichlorophosphate; at 0 ℃;

With tributyl-amine; tri(n-butyl)ammonium pyrophosphate; In acetonitrile;

DOI:10.1080/15257770.2020.1738457

Reference yield:

ATP (56-65-5,896506-78-8) → Inosine 5'-triphosphate (132-06-9)

Guidance literature:

With water; adenosine deaminase; Enzymatic reaction;

DOI:10.1002/anie.201502315

Reference yield:

ATP (56-65-5,896506-78-8) → inosine 5'-triphosphate (132-06-9,76617-73-7)

Guidance literature:

With sodium acetate; acetic acid; sodium nitrite;

upstream raw materials:

ATP

Inosine

Downstream raw materials:

phosphoric acid

3'-O-(N-methylanthraniloyl)-inosine 5'-triphosphate

C₁₈H₂₁N₅O₁₂P₂

bis-MANT-IDP

Refernces

• 1、 Senthilvelan, Annamalai,Shanmugasundaram, Muthian,Kore, Anilkumar R.. "Highly regioselective methylation of inosine nucleotide: an efficient synthesis of 7-methylinosine nucleotide". . p. 1011 - 1019. Retrieved 2020/03/30.