Chlorodiisopropylsilane

Base Information

• Chemical Name: Chlorodiisopropylsilane
• CAS No.: 2227-29-4
• Molecular Formula: C6H15ClSi
• Molecular Weight: 150.724
• Hs Code.: 29319090
• European Community (EC) Number: 627-650-3
• UNII: DVG177547J
• DSSTox Substance ID: DTXSID40883814
• Mol file: 2227-29-4.mol

Synonyms:Diisopropylchlorosilane;2227-29-4;Chlorodiisopropylsilane;chloro-di(propan-2-yl)silicon;Silane, chlorobis(1-methylethyl)-;UNII-DVG177547J;DVG177547J;chlorobis(propan-2-yl)silane;Chlorobis(1-methylethyl)silane;Silane, chloro(diisopropyl)-;Chlorodiisopropylsilane, 99%;SCHEMBL296389;DTXSID40883814;Silane,chlorobis(1-methylethyl)-;CHLORODIISOPROPYLSILANE [MI];MFCD00054896;AKOS006222977;FS-5365;FT-0634149;S06775;EN300-7587636;J-014619

Chemical Property of Chlorodiisopropylsilane

Chemical Property:

• Refractive Index: n20/D 1.429(lit.)
• Boiling Point: 134.2 °C at 760 mmHg
• Flash Point: 22.2 °C
• PSA: 0.00000
• Density: 0.883 g/mL at 25 °C(lit.)
• LogP: 2.76900
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: generally sol organic solvents; reacts with alcohols, ammonia,and water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 149.0553297
• Heavy Atom Count: 8
• Complexity: 53.5

Purity/Quality:

99.5% ^*data from raw suppliers

Chlorodiisopropylsilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 10-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C)[Si](C(C)C)Cl
• Physical properties: bp 150–153°C,bp 54–55°C/45 mmHg; d 0.872 gmL?1
• Uses: Intramolecular hydrosilylation is also possible within β-diisopropylsilyloxy esters (13), constituting an exceptionally mild method for reducing ester groups to the aldehyde oxidation level (eq 4).The derivatives (13) may be synthesized from β-hydroxy esters (12) as described above for the analogous ketones. Treatment with fluoride ions (but not Lewis acids) induces hydride transfer to give alkoxysiladioxanes (14) in excellent yields (≥95%). Although usually performed in dichloromethane, the hydrosilylation may also be accomplished with ethyl acetate as solvent, providing strong evidence for intramolecularity.

Technology Process of Chlorodiisopropylsilane

There total 4 articles about Chlorodiisopropylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

di-isopropylsilane (18209-66-0) → chlorodiisopropylsilane (2227-29-4)

Guidance literature:

With hydrogenchloride; In diethylene glycol dimethyl ether; at 60 ℃; for 8h; Temperature; Solvent;

Reference yield: 75.0%

isopropyl chloride (75-29-6) → chlorodiisopropylsilane (2227-29-4)

Guidance literature:

isopropyl chloride; With magnesium; In tetrahydrofuran; at 40 - 65 ℃; Inert atmosphere;

With trichlorosilane; In tetrahydrofuran; hexane; at -10 - 0 ℃; Temperature; Inert atmosphere;

Reference yield:

isopropylmagnesium bromide (920-39-8) → chlorodiisopropylsilane (2227-29-4)

Guidance literature:

With trichlorosilane; In diethyl ether; for 18h; Yield given; Heating;

DOI:10.1021/ja00032a028

upstream raw materials:

isopropylmagnesium chloride

isopropyl chloride

isopropylmagnesium bromide

di-isopropylsilane

Downstream raw materials:

(Z)-(2S,3R,8R)-3-(tert-Butyl-diphenyl-silanyloxy)-8-diisopropylsilanyloxy-2-ethyl-9-methylene-2,3,4,7,8,9-hexahydro-oxonine

2-(4-tert-Butyl-2,6-diisopropyl-phenyl)-1,1-diisopropyl-disilane

1-tert-Butyl-2,2-diisopropyl-1,1-bis-(2,4,6-trimethyl-phenyl)-disilane

(E)-1-diisopropylsilyloxy-3-phenylprop-2-ene

Refernces

• 1、 Sturm, Alexander G.,Schweizer, Julia I.,Meyer, Lioba,Santowski, Tobias,Auner, Norbert,Holthausen, Max C.. "Lewis Base Catalyzed Selective Chlorination of Monosilanes". supporting information. p. 17796 - 17801. Retrieved 2018/11/23.
• 2、 Kawakami, Yoshiteru,Sakuma, Yoshinobu,Wakuda, Takashi,Nakai, Tatsuya,Shirasaka, Masayoshi,Kabe, Yoshio. "Hydrogen-bonding 3D networks by polyhedral organosilanols: Selective inclusion of hydrocarbons in open frameworks". experimental part. p. 3281 - 3288. Retrieved 2010/09/06.