cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate

Base Information

• Chemical Name: cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate
• CAS No.: 345652-52-0
• Molecular Formula: C₂₂H₂₈N₂O₂
• Molecular Weight: 352.477
• Mol file: 345652-52-0.mol

Synonyms:cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate

Chemical Property of cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate

There total 2 articles about cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylic acid sodium salt → cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate (345652-52-0)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; water; benzene;

Reference yield:

cis 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylic acid sodium salt + methyl iodide (74-88-4) → cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate (345652-52-0)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; ice-water; water;

Reference yield:

cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate (345652-52-0) + chloroform (67-66-3,8013-54-5) + propionic acid (802294-64-0,79-09-4) → trans-methyl 3-methyl-4-[N-(1-oxopropyl)-N-phenylamino]-1-(2-phenylethyl)-4-piperidinecarboxylate ethanedioate (61087-48-7,61087-50-1,61380-39-0,61380-41-4,73025-44-2,73025-45-3,73025-48-6,73025-49-7)

Guidance literature:

In water; isopropyl alcohol;

upstream raw materials:

methyl iodide

Downstream raw materials:

trans-methyl 3-methyl-4-[N-(1-oxopropyl)-N-phenylamino]-1-(2-phenylethyl)-4-piperidinecarboxylate ethanedioate

Refernces

• 1、 -. "N-(4-piperidinyl)-N-phenylamides and -carbamates". . . Retrieved 2008/06/13.