C₂₆H₂₁Cl₂NO₇

Base Information

• Chemical Name: C₂₆H₂₁Cl₂NO₇
• CAS No.: 1295651-03-4
• Molecular Formula: C₂₆H₂₁Cl₂NO₇
• Molecular Weight: 530.361
• Mol file: 1295651-03-4.mol

Synonyms:C₂₆H₂₁Cl₂NO₇

Chemical Property of C₂₆H₂₁Cl₂NO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₁Cl₂NO₇

There total 2 articles about C₂₆H₂₁Cl₂NO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(R)-2-[4-(3,5-dichloro-pyridin-2-yloxy)phenoxy]propionic acid + propargyl alcohol (107-19-7) + (R)-2-(4-hydroxyphenoxy)propionic acid (94050-90-5) → C26H21Cl2NO7 (1295651-03-4)

Guidance literature:

(R)-2-[4-(3,5-dichloro-pyridin-2-yloxy)phenoxy]propionic acid; With dmap; 1,3,5-trichloro-2,4,6-triazine; benzyltriphenylphosphonium bromide; In acetone; at 25 ℃; for 1.16667h;

(R)-2-(4-hydroxyphenoxy)propionic acid; In acetone; at 25 ℃; for 2h;

propargyl alcohol; In acetone; at 25 ℃;

DOI:10.1016/j.cclet.2010.12.001

Reference yield:

2-Fluoro-3,5-dichloropyridine (823-56-3) → C26H21Cl2NO7 (1295651-03-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide

2.1: dmap; 1,3,5-trichloro-2,4,6-triazine; benzyltriphenylphosphonium bromide / acetone / 1.17 h / 25 °C

2.2: 2 h / 25 °C

2.3: 25 °C

With dmap; 1,3,5-trichloro-2,4,6-triazine; benzyltriphenylphosphonium bromide; potassium carbonate; In N,N-dimethyl-formamide; acetone;

DOI:10.1016/j.cclet.2010.12.001

upstream raw materials:

propargyl alcohol

(R)-2-(4-hydroxyphenoxy)propionic acid

2-Fluoro-3,5-dichloropyridine

Refernces