1,1,1,2-Tetrafluoro-2-(trifluoromethoxy)ethane

Base Information

• Chemical Name: 1,1,1,2-Tetrafluoro-2-(trifluoromethoxy)ethane
• CAS No.: 2356-62-9
• Molecular Formula: C3HF7O
• Molecular Weight: 186.029
• Hs Code.: 2909199090
• DSSTox Substance ID: DTXSID40946332
• Nikkaji Number: J958.182K
• Mol file: 2356-62-9.mol

Synonyms:2356-62-9;1,1,1,2-tetrafluoro-2-(trifluoromethoxy)ethane;1,2,2,2-Tetrafluoroethyl trifluoromethyl ether;Ethane, 1,1,1,2-tetrafluoro-2-(trifluoromethoxy)-;C3HF7O;Ethane,1,1,1,2-tetrafluoro-2-(trifluoromethoxy)-;SCHEMBL891882;UDKWMTKIRQSDHF-UHFFFAOYSA-;DTXSID40946332;HFE-227;UDKWMTKIRQSDHF-UHFFFAOYSA-N;MFCD01320709;AKOS006227603;FT-0606164;1,2,2,2-tetrafluoroethyl trifluoro-methyl ether;A816774;1,1,1,2-tetrakis(fluoranyl)-2-(trifluoromethyloxy)ethane;InChI=1/C3HF7O/c4-1(2(5,6)7)11-3(8,9)10/h1H

Chemical Property of 1,1,1,2-Tetrafluoro-2-(trifluoromethoxy)ethane

Chemical Property:

• Vapor Pressure: 3000mmHg at 25°C
• Refractive Index: 1.24
• Boiling Point: -9°C
• PSA: 9.23000
• Density: 1.512 g/cm³
• LogP: 2.38070
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 1
• Exact Mass: 185.99156179
• Heavy Atom Count: 11
• Complexity: 123

Purity/Quality:

98%Min ^*data from raw suppliers

1,2,2,2-Tetrafluoroethyl trifluoromethyl ether 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 23-38

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(F)(F)F)(OC(F)(F)F)F

Technology Process of 1,1,1,2-Tetrafluoro-2-(trifluoromethoxy)ethane

There total 2 articles about 1,1,1,2-Tetrafluoro-2-(trifluoromethoxy)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

1,1-difluoro-2-(trifluoromethoxy)ethane (84011-15-4) → 1,2,2,2-Tetrafluoroethyl trifluoromethyl ether (2356-62-9) + pentafluoroethyl trifluoromethyl ether (665-16-7) + 2,2,2-trifluoroethyl trifluoromethyl ether (20193-67-3) + 1,2,2-Trifluoroethyl Trifluoromethyl Ether (84011-06-3)

Guidance literature:

With fluorine; sodium fluoride; Further byproducts given;

Reference yield:

hypofluorous acid trifluoromethyl ester (373-91-1) + 1,2-dichloro-1,2-difluoroethene (598-88-9) + 1,1,2-trifluoroethylene (359-11-5) → 1,2,2,2-Tetrafluoroethyl trifluoromethyl ether (2356-62-9) + trifluoromethyl-1H-pentafluoroethyl ether (2356-61-8) + 1-trifluoromethoxy-1,2-dichlorotrifluoroethane (2356-53-8)

Guidance literature:

In trichlorofluoromethane; at -105 ℃; Rate constant; Product distribution; competition with ClFC=CFCl and FHC=CF₂, relative addition rates and orientation ratios;

DOI:10.1021/jo00125a033

upstream raw materials:

1,1-difluoro-2-(trifluoromethoxy)ethane

hypofluorous acid trifluoromethyl ester

1,2-dichloro-1,2-difluoroethene

1,1,2-trifluoroethylene

Refernces

• 1、 Sekiya, Akira,Ueda, Kunimasa. "Synthesis of Perfluoroethylmethylether by Direct Fluorination". . p. 609 - 612. Retrieved 2007/10/02.