Diphenyl succinate

Base Information

• Chemical Name: Diphenyl succinate
• CAS No.: 621-14-7
• Molecular Formula: C16H14 O4
• Molecular Weight: 270.285
• Hs Code.: 2917190090
• European Community (EC) Number: 633-095-8
• NSC Number: 2623
• UNII: 7FQX7J39BM
• DSSTox Substance ID: DTXSID4060731
• Nikkaji Number: J136.490A
• Wikidata: Q81989176
• Mol file: 621-14-7.mol

Synonyms:Diphenyl succinate;621-14-7;diphenyl butanedioate;Butanedioic acid, diphenyl ester;Succinic acid, diphenyl ester;Butanedioic acid, 1,4-diphenyl ester;7FQX7J39BM;butanedioic acid diphenyl ester;NSC 2623;NSC-2623;UNII-7FQX7J39BM;Succinic acid diphenyl ester;SCHEMBL43742;DTXSID4060731;NSC2623;1,4-DIPHENYL BUTANEDIOATE;AKOS004908152;FT-0654055;A833588

Chemical Property of Diphenyl succinate

Chemical Property:

• Vapor Pressure: 3.36E-07mmHg at 25°C
• Melting Point: 121°C
• Refractive Index: 1.5447 (estimate)
• Boiling Point: 418.1°C at 760 mmHg
• Flash Point: 211.6°C
• PSA: 52.60000
• Density: 1.198g/cm³
• LogP: 2.97780
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 270.08920892
• Heavy Atom Count: 20
• Complexity: 282

Purity/Quality:

99% ^*data from raw suppliers

DIPHENYL SUCCINATE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC(=O)CCC(=O)OC2=CC=CC=C2

Technology Process of Diphenyl succinate

There total 14 articles about Diphenyl succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

succinoyl dichloride (543-20-4) + acetyl chloride (75-36-5) → diphenyl succinate (621-14-7)

Guidance literature:

With tetrabutyl-ammonium chloride; sodium hydroxide; In dichloromethane; water; at 0 ℃; for 0.0833333h;

DOI:10.1080/00397911.2011.584007

Reference yield: 93.0%

succinic acid anhydride (108-30-5) + phenol (108-95-2,27073-41-2) → diphenyl succinate (621-14-7)

Guidance literature:

Sulfate; tin(IV) oxide; In acetonitrile; at 20 ℃; for 6h;

DOI:10.1080/00397910701354723

Reference yield: 86.0%

(E)-but-2-enedioic acid diphenyl ester (6338-19-8) → diphenyl succinate (621-14-7)

Guidance literature:

With [CpCoCpNMe₂][OTf]; tert-butylammonium hexafluorophosphate(V); toluene-4-sulfonic acid; In 1,2-dimethoxyethane; for 20h; Reagent/catalyst; Kinetics; Electrochemical reaction;

DOI:10.1021/jacs.1c03335

upstream raw materials:

succinoyl dichloride

phenol

succinic acid

5,6-Diphenyl-2,3-dihydro-[1,4]dioxine

Downstream raw materials:

succinic acid bis(p-nitrophenyl ester)

Refernces

• 1、 Kane, Staci R.,Beller, Harry R.,Legler, Tina C.,Anderson, Robert T.. "Biochemical and genetic evidence of benzylsuccinate synthase in toluene-degrading, ferric iron-reducing Geobacter metallireducens". . p. 149 - 154. Retrieved 2002.
• 2、 Le, Son Dinh,Nishimura, Shun,Ebitani, Kohki. "Direct esterification of succinic acid with phenol using zeolite beta catalyst". . p. 20 - 23. Retrieved 2019/01/16.
• 3、 Satam, Jitendra R.,Gawande, Manoj B.,Deshpande, Sameer S.,Jayaram, Radha V.. "SO42-/SnO2: Efficient, chemoselective, and reusable catalyst for acylation of alcohols, phenols, and amines at room temperature". . p. 3011 - 3020. Retrieved 2008/02/12.