PROTOPORPHYRINATO ZINC

Base Information

• Chemical Name: PROTOPORPHYRINATO ZINC
• CAS No.: 15442-64-5
• Molecular Formula: C34H30 N4 O4 Zn . 2 H
• Molecular Weight: 626.042
• European Community (EC) Number: 239-455-7
• Wikipedia: Zinc_protoporphyrin
• NCI Thesaurus Code: C123793
• Mol file: 15442-64-5.mol

Synonyms:Protoporphyrin,zinc deriv. (6CI); Zinc, [dihydrogen3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]- (8CI); Zinc,[dihydrogen protoporphyrin IX-ato(2-)]- (7CI); Zincate(2-),[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24]-,dihydrogen, (SP-4-2)-; Zincate(2-),[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-kN21,kN22,kN23,kN24]-, dihydrogen, (SP-4-2)-(9CI); 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-,zinc complex; Zinc protoporphyrin; Zinc protoporphyrin IX; Zinc(II)protoporphyrin IX

Chemical Property of PROTOPORPHYRINATO ZINC

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1128.5°Cat760mmHg
• Flash Point: 636.3°C
• PSA: 109.18000
• Density: g/cm³
• LogP: 3.60970
• Storage Temp.: Store at RT
• Water Solubility.: Insoluble in water. Soluble in ethanol, and DMSO, pyridine, or dimethyl formamide.
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 8
• Exact Mass: 624.171497
• Heavy Atom Count: 43
• Complexity: 1580

Purity/Quality:

98%min ^*data from raw suppliers

ZincProtoporphyrin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C(=C3CCC(=O)O)C)CCC(=O)O.[Zn+2]
• Uses: Zinc Protoporphyrin is a metabolite formed during biosynthesis and is used to evaluate iron nutrition and metabolism.

Technology Process of PROTOPORPHYRINATO ZINC

There total 6 articles about PROTOPORPHYRINATO ZINC which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

zinc(II) acetate dihydrate (5970-45-6) + protoporphyrin IX (553-12-8) → zinc protoporphyrin (15442-64-5)

Guidance literature:

In N,N-dimethyl-formamide; for 2h; Reflux;

DOI:10.1016/j.ica.2017.06.069

Reference yield:

protoporphyrin IX (553-12-8) → zinc protoporphyrin (15442-64-5)

Guidance literature:

With zinc(II) chloride; In dichloromethane; water; for 2h; Sonication;

DOI:10.5012/bkcs.2010.31.6.1633

Reference yield:

zinc diacetate (557-34-6) + protoporphyrin IX (553-12-8) → zinc protoporphyrin (15442-64-5)

Guidance literature:

In dimethyl sulfoxide; at 60 ℃; for 24h;

DOI:10.3390/jpm11020136

upstream raw materials:

protoporphyrin IX

protoporphyrin IX

zinc(II) acetate dihydrate

protoporphyrin IX

Refernces

• 1、 Gao, Shanghui,Islam, Rayhanul,Fang, Jun. "Tumor environment-responsive hyaluronan conjugated zinc protoporphyrin for targeted anticancer photodynamic therapy". . p. 1 - 15. Retrieved 2021.
• 2、 Patwari, Jayita,Chatterjee, Arka,Sardar, Samim,Lemmens, Peter,Pal, Samir Kumar. "Ultrafast dynamics in co-sensitized photocatalysts under visible and NIR light irradiation". . p. 10418 - 10429. Retrieved 2018/04/27.