N-(2-Aminoethyl)acrylamide

Base Information

• Chemical Name: N-(2-Aminoethyl)acrylamide
• CAS No.: 23918-29-8
• Molecular Formula: C₅H₁₀N₂O
• Molecular Weight: 114.147
• Hs Code.: 2924199090
• Mol file: 23918-29-8.mol

Synonyms:(2-Aminoethyl)acrylamide;2-Propenamide,N-(2-aminoethyl)-;Acrylamide,N-(2-aminoethyl)- (8CI);

Chemical Property of N-(2-Aminoethyl)acrylamide

Chemical Property:

• Vapor Pressure: 0.00134mmHg at 25°C
• Refractive Index: 1.466
• Boiling Point: 297.502 °C at 760 mmHg
• PKA: 14.48±0.46(Predicted)
• Flash Point: 133.725 °C
• PSA: 58.61000
• Density: 0.986 g/cm³
• LogP: 0.78790

Purity/Quality:

99%, ^*data from raw suppliers

N-(2-Aminoethyl)acrylamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-Aminoethyl)acrylamide

There total 6 articles about N-(2-Aminoethyl)acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H17N3O4 → N-[beta-aminoethyl]acrylamide (23918-29-8)

Guidance literature:

With γ-glutamyl transpeptidase; In water-d2; at 37 ℃; pH=7.4; Enzymatic reaction;

Reference yield:

tert-butyl N-[2-(propyl-2-enamine)ethyl]carbamate (637005-34-6) → N-[beta-aminoethyl]acrylamide (23918-29-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

tert-butyl (2-acrylamidoethyl)carbamate (165196-44-1) → N-[beta-aminoethyl]acrylamide (23918-29-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/j.ejmech.2021.113432

upstream raw materials:

ethylenediamine

acryloyl chloride

N-(2-aminoethyl)prop-2-enamide hydrochloride

tert-butyl N-[2-(propyl-2-enamine)ethyl]carbamate

Refernces

• 1、 Shan, Huifang,Ma, Xinyu,Yan, Guoyi,Luo, Meng,Zhong, Xinxin,Lan, Suke,Yang, Jie,Liu, Yuanyuan,Pu, Chunlan,Tong, Yu,Li, Rui. "Discovery of a novel covalent CDK4/6 inhibitor based on palbociclib scaffold". . . Retrieved 2021/04/15.
• 2、 -. "Biphenyl compound as immunoregulator and applications of same". Paragraph 0406-0410. . Retrieved 2020/03/17.