Carsalam

Base Information

• Chemical Name: Carsalam
• CAS No.: 2037-95-8
• Molecular Formula: C8H5NO3
• Molecular Weight: 163.133
• Hs Code.: 2934999090
• European Community (EC) Number: 606-541-4
• NSC Number: 758885,36166
• UNII: 685H843ULU
• DSSTox Substance ID: DTXSID3046584
• Nikkaji Number: J7.854I
• Wikidata: Q27264215
• NCI Thesaurus Code: C77338
• ChEMBL ID: CHEMBL1720051
• Mol file: 2037-95-8.mol

Synonyms:1,3-benzoxazine-2,4-dione;2H-1,3-benzoxazin-4(3H)-one;2H-1,3-benzoxazine-2,4(3H)-dione;carsalam

Chemical Property of Carsalam

Chemical Property:

• Vapor Pressure: 0.73-1.27Pa at 89.94-107.94℃
• Melting Point: 228-232 °C(lit.)
• Refractive Index: 1.585
• PKA: 9.16±0.20(Predicted)
• PSA: 63.07000
• Density: 1.402g/cm³
• LogP: 0.48130
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 163.026943022
• Heavy Atom Count: 12
• Complexity: 226

Purity/Quality:

99% ^*data from raw suppliers

Carsalam ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=O)NC(=O)O2
• Uses: analgesic

Technology Process of Carsalam

There total 12 articles about Carsalam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosgene (75-44-5) + salicylamide (65-45-2) → salicylonitrile (611-20-1) + 1,3-benzoxazine-2,4-dione (2037-95-8)

Guidance literature:

With pyridine;

Reference yield:

pyridine (110-86-1) + phosgene (75-44-5) + salicylamide (65-45-2) → salicylonitrile (611-20-1) + 1,3-benzoxazine-2,4-dione (2037-95-8)

Guidance literature:

Reference yield:

phosgene (75-44-5) + salicylamide (65-45-2) → salicylonitrile (611-20-1) + 1,3-benzoxazine-2,4-dione (2037-95-8)

Guidance literature:

upstream raw materials:

pyridine

phosgene

salicylamide

urea

Downstream raw materials:

3-methyl-benzo<1,3>oxazine-2,4-dione

3-ethyl-3,4-dihydro-2H-1,3-benzoxazine-2,4-dione

3-benzyl-2H-benzo[e][1,3]oxazine-2,4(3H)-dione

3-(4-ethylbenzoyl)-2H-benz[e][1,3]oxazine-2,4(3H)-dione

Refernces