Technology Process of (2R,3S,4S)-3-acetoxy-4-allyloxy-1-benzyl-2-(p-methoxybenzyl)pyrrolidine
There total 15 articles about (2R,3S,4S)-3-acetoxy-4-allyloxy-1-benzyl-2-(p-methoxybenzyl)pyrrolidine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: NaIO4
2: NH2OH*HCl, pyridine
3: pyridine
4: LiAlH4 / diethyl ether
5: 1.) HCl, H2O, 2.) HBr / 1.) MeOH, reflux, 2.) 10 deg C
6: KOH, H2O / methanol
7: HClO4 / CHCl3 / 60 °C
8: 1.) Et3N, 2.) pyridine / 1.) CHCl3
With
pyridine; hydrogenchloride; potassium hydroxide; sodium periodate; lithium aluminium tetrahydride; perchloric acid; hydroxylamine hydrochloride; water; hydrogen bromide; triethylamine;
In
methanol; diethyl ether; chloroform;
DOI:10.1039/c39830000486
- Guidance literature:
-
Multi-step reaction with 6 steps
1: pyridine
2: LiAlH4 / diethyl ether
3: 1.) HCl, H2O, 2.) HBr / 1.) MeOH, reflux, 2.) 10 deg C
4: KOH, H2O / methanol
5: HClO4 / CHCl3 / 60 °C
6: 1.) Et3N, 2.) pyridine / 1.) CHCl3
With
pyridine; hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; perchloric acid; water; hydrogen bromide; triethylamine;
In
methanol; diethyl ether; chloroform;
DOI:10.1039/c39830000486
- Guidance literature:
-
Multi-step reaction with 7 steps
1: NH2OH*HCl, pyridine
2: pyridine
3: LiAlH4 / diethyl ether
4: 1.) HCl, H2O, 2.) HBr / 1.) MeOH, reflux, 2.) 10 deg C
5: KOH, H2O / methanol
6: HClO4 / CHCl3 / 60 °C
7: 1.) Et3N, 2.) pyridine / 1.) CHCl3
With
pyridine; hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; perchloric acid; hydroxylamine hydrochloride; water; hydrogen bromide; triethylamine;
In
methanol; diethyl ether; chloroform;
DOI:10.1039/c39830000486