4-methylphenyl 2-naphthyl sulfide

Base Information

• Chemical Name: 4-methylphenyl 2-naphthyl sulfide
• CAS No.: 52258-16-9
• Molecular Formula: C₁₇H₁₄S
• Molecular Weight: 250.364
• Mol file: 52258-16-9.mol

Synonyms:4-methylphenyl 2-naphthyl sulfide

Chemical Property of 4-methylphenyl 2-naphthyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methylphenyl 2-naphthyl sulfide

There total 37 articles about 4-methylphenyl 2-naphthyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

S-(p-tolyl) naphthalene-2-carbothioate → 4-methylphenyl 2-naphthyl sulfide (52258-16-9)

Guidance literature:

With 1,3-bis-(diphenylphosphino)propane; sodium carbonate; magnesium; nickel dichloride; In toluene; at 150 ℃; for 36h; Sealed tube; Inert atmosphere;

DOI:10.1002/chem.201705842

Reference yield: 96.0%

4-tolyl iodide (624-31-7) + 2-Naphthalenethiol (91-60-1) → 4-methylphenyl 2-naphthyl sulfide (52258-16-9)

Guidance literature:

With iron(III) chloride; sodium t-butanolate; N,N`-dimethylethylenediamine; In toluene; at 135 ℃; for 24h;

DOI:10.1002/anie.200705668

Reference yield: 95.0%

para-thiocresol (106-45-6) + β-naphthol (135-19-3) → 4-methylphenyl 2-naphthyl sulfide (52258-16-9)

Guidance literature:

With trifluorormethanesulfonic acid; In benzene; at 50 ℃; for 3h;

DOI:10.1055/s-1989-27444

upstream raw materials:

para-bromotoluene

para-thiocresol

β-naphthol

4-tolyl iodide

Downstream raw materials:

10-methylbenzonaphtho<1,2-b>thiophene

2-methylbenzonaphtho<2,3-d>thiophene

α-Cyano-4-(2-naphthylthio)phenylacetaldehyd

2-Naphthylthiophenylacetonitril

Refernces

• 1、 Wang, Cheng-Yi,Tian, Rui,Zhu, Yong-Ming. "Ni-catalyzed C–S bond cleavage of aryl 2-pyridyl thioethers coupling with alkyl and aryl thiols". . . Retrieved 2021/09/29.
• 2、 Zhou, Jing-Ya,Zhu, Yong-Ming. "Forging C?S(Se) Bonds by Nickel-catalyzed Decarbonylation of Carboxylic Acid and Cleavage of Aryl Dichalcogenides". . p. 2452 - 2461. Retrieved 2021/06/28.