Technology Process of gamma-Cyano-gamma-ethylbenzenebutanoic acid
There total 6 articles about gamma-Cyano-gamma-ethylbenzenebutanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / methanol; water / 1 h / 20 °C / Inert atmosphere
2: N-benzyl-trimethylammonium hydroxide / methanol; 1,4-dioxane / 3 h / 0 - 20 °C / Inert atmosphere
3: sodium hydroxide / methanol; water / 3 h / 50 °C / Inert atmosphere
With
N-benzyl-trimethylammonium hydroxide; potassium carbonate; sodium hydroxide;
In
1,4-dioxane; methanol; water;
2: |Michael Addition;
DOI:10.1002/adsc.201501013
- Guidance literature:
-
With
sodium hydroxide;
In
methanol; water;
at 50 ℃;
for 3h;
Inert atmosphere;
DOI:10.1002/adsc.201501013
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-benzyl-trimethylammonium hydroxide / methanol; 1,4-dioxane / 3 h / 0 - 20 °C / Inert atmosphere
2: sodium hydroxide / methanol; water / 3 h / 50 °C / Inert atmosphere
With
N-benzyl-trimethylammonium hydroxide; sodium hydroxide;
In
1,4-dioxane; methanol; water;
1: |Michael Addition;
DOI:10.1002/adsc.201501013
