1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone

Base Information

• Chemical Name: 1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone
• CAS No.: 171080-06-1
• Molecular Formula: C₂₂H₁₉NO₂
• Molecular Weight: 329.398
• Mol file: 171080-06-1.mol

Synonyms:1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone

Chemical Property of 1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone

There total 8 articles about 1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-styrenyloxytrimethylsilane (13735-81-4) + phenylglyoxal hydrate (1074-12-0) + aniline (62-53-3) → 1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone (171080-06-1)

Guidance literature:

With tetrafluoroboric acid; water; sodium dodecyl-sulfate; at 25 ℃; for 1.5h;

Reference yield:

1-styrenyloxytrimethylsilane (13735-81-4) + (E)-1-phenyl-2-(phenylimino)ethanone (66749-86-8) → 1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone (171080-06-1)

Guidance literature:

With tetrafluoroboric acid; water; In isopropyl alcohol; at 0 ℃; for 3.5h; Yield given;

DOI:10.1055/s-1999-2789

Reference yield:

phenylglyoxal hydrate (1074-12-0) → 1,4-diphenyl-2-(N-phenylamino)-1,4-butadienone (171080-06-1)

Guidance literature:

Multi-step reaction with 2 steps

1: propan-2-ol / 0.5 h / -40 °C

2: HBF₄, H₂O / propan-2-ol / 3.5 h / 0 °C

With tetrafluoroboric acid; water; In isopropyl alcohol;

DOI:10.1055/s-1999-2789

upstream raw materials:

1,4-diphenyl-but-2-ene-1,4-dione

aniline

1-styrenyloxytrimethylsilane

phenylglyoxal hydrate

Downstream raw materials:

1,4-diphenyl-but-2-ene-1,4-dione

Refernces

• 1、 Akiyama, Takahiko,Takaya, Jim,Kagoshima, Hirotaka. "Bronsted Acid-Catalyzed Mannich-Type Reactions in Aqueous Media". . p. 338 - 347. Retrieved 2007/10/03.
• 2、 Akiyama, Takahiko,Takaya, Jun,Kagoshima, Hirotaka. "HBF4 catalyzed Mannich-type reaction in aqueous media". . p. 1045 - 1048. Retrieved 2007/10/03.