alpha-(Ethylaminomethyl)-p-hydroxybenzyl alcohol

Base Information

• Chemical Name: alpha-(Ethylaminomethyl)-p-hydroxybenzyl alcohol
• CAS No.: 4232-09-1
• Molecular Formula: C₁₀H₁₅NO₂
• Molecular Weight: 181.235
• Hs Code.: 2922509090
• DSSTox Substance ID: DTXSID10962423
• Nikkaji Number: J66.002G
• Mol file: 4232-09-1.mol

Synonyms:Ethylnorsynephrine;BRN 3258858;4232-09-1;alpha-(Ethylaminomethyl)-p-hydroxybenzyl alcohol;alpha-((Ethylamino)methyl)-4-hydroxybenzenemethanol;Benzenemethanol, alpha-((ethylamino)methyl)-4-hydroxy-;BENZYL ALCOHOL, alpha-((ETHYLAMINO)METHYL)-p-HYDROXY-;4-[2-(ethylamino)-1-hydroxyethyl]phenol;SCHEMBL6457448;DTXSID10962423;LS-42973;3-13-00-02241 (Beilstein Handbook Reference);alpha-[(Ethylamino)methyl]-p-hydroxybenzyl alcohol

Chemical Property of alpha-(Ethylaminomethyl)-p-hydroxybenzyl alcohol

Chemical Property:

• Vapor Pressure: 1.5E-05mmHg at 25°C
• Boiling Point: 351.7°Cat760mmHg
• Flash Point: 155.5°C
• PSA: 52.49000
• Density: 1.127g/cm³
• LogP: 1.42600
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 181.110278721
• Heavy Atom Count: 13
• Complexity: 133

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNCC(C1=CC=C(C=C1)O)O

Technology Process of alpha-(Ethylaminomethyl)-p-hydroxybenzyl alcohol

There total 2 articles about alpha-(Ethylaminomethyl)-p-hydroxybenzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethylamino-1-(4-hydroxy-phenyl)-ethanone (99075-26-0) → 2-ethylamino-1-(4-hydroxy-phenyl)-ethanol (4232-09-1)

Guidance literature:

With palladium on activated charcoal; water; Hydrogenation;

DOI:10.1021/ja01227a004

Reference yield:

4'-benzoyloxy-2-bromoacetophenone (5324-15-2) → 2-ethylamino-1-(4-hydroxy-phenyl)-ethanol (4232-09-1)

Guidance literature:

Multi-step reaction with 2 steps

1: isopropyl alcohol

2: water; palladium/charcoal / Hydrogenation

With palladium on activated charcoal; water; isopropyl alcohol;

DOI:10.1021/ja01227a004

upstream raw materials:

2-ethylamino-1-(4-hydroxy-phenyl)-ethanone

4'-benzoyloxy-2-bromoacetophenone