2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-3-perdeuterostearyl-sn-glycer-1-yl) phosphate

Base Information

• Chemical Name: 2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-3-perdeuterostearyl-sn-glycer-1-yl) phosphate
• CAS No.: 1187738-20-0
• Molecular Formula: C₇₇H₁₂₂NO₁₀PSi₂
• Molecular Weight: 1378.41
• Mol file: 1187738-20-0.mol

Synonyms:2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-3-perdeuterostearyl-sn-glycer-1-yl) phosphate

Chemical Property of 2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-3-perdeuterostearyl-sn-glycer-1-yl) phosphate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-3-perdeuterostearyl-sn-glycer-1-yl) phosphate

There total 1 articles about 2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-3-perdeuterostearyl-sn-glycer-1-yl) phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-sn-glycer-1-yl) phosphate (1187738-15-3) + deuterated octadecanoic acid (17660-51-4,211443-83-3) → 2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-3-perdeuterostearyl-sn-glycer-1-yl) phosphate (1187738-20-0)

Guidance literature:

deuterated octadecanoic acid; With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 0.166667h;

2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-sn-glycer-1-yl) phosphate; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1016/j.tet.2009.06.085

Reference yield: 87.0%

2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-3-perdeuterostearyl-sn-glycer-1-yl) phosphate (1187738-20-0) → bis-(3-perdeuterostearyl-sn-glycer-1-yl) phosphate ammonium salt

Guidance literature:

With tetrabutyl ammonium fluoride; water; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.tet.2009.06.085

upstream raw materials:

2-cyanoethyl bis-(2-O-(tert-butyldiphenylsilyl)-sn-glycer-1-yl) phosphate

deuterated octadecanoic acid

Refernces