p-Phenylenediamine dihydrochloride

Base Information

• Chemical Name: p-Phenylenediamine dihydrochloride
• CAS No.: 624-18-0
• Molecular Formula: C6H10Cl2N2
• Molecular Weight: 181.065
• Hs Code.: 29215119
• European Community (EC) Number: 259-926-0
• NSC Number: 112725
• DSSTox Substance ID: DTXSID50968823
• Mol file: 624-18-0.mol

Synonyms:1,4-Benzenediamine,dihydrochloride (9CI);p-Phenylenediamine, dihydrochloride (8CI);1,4-Phenylenediamine dihydrochloride;1,4-Benzenediamine,hydrochloride (1:2);C.I. Oxidation Base 10A;Durafur Black RC;Fourrine 64;Fourrine DS;Pelagol CD;Pelagol Grey CD;

Chemical Property of p-Phenylenediamine dihydrochloride

Chemical Property:

• Appearance/Colour: Off-white crystal powder
• Vapor Pressure: 0.00817mmHg at 25°C
• Melting Point: >200 °C
• Boiling Point: 267.4 °C at 760 mmHg
• Flash Point: 135.9 °C
• PSA: 52.04000
• Density: 1.15 g/cm3
• LogP: 3.61740
• Storage Temp.: Store below +30°C.
• Solubility.: Methanol (Slightly), Water (Slightly)
• Water Solubility.: >=10 g/100 mL at 21 ºC
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 144.0454260
• Heavy Atom Count: 9
• Complexity: 54.9

Purity/Quality:

99% ^*data from raw suppliers

P-PhenylenediamineDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T, N
• Hazard Codes: T,N
• Statements: 23/24/25-36-43-50/53
• Safety Statements: 28-36/37-45-60-61-28A

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1N)N.Cl
• Uses: Dihydrochloride salt of 1,4-Phenylenediamine (P319845). A hair dye component, paraphenylenediamine, as a contact allergen for treatment of inflammatory diseases. P-Phenylenediamine Dihydrochloride can be used for coloring of keratinous materials using at least an self-?oxidizing dye or a blue, purple or green oxidative dye and at least one fluorescent dye.

Technology Process of p-Phenylenediamine dihydrochloride

There total 6 articles about p-Phenylenediamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,4-phenylenediamine (106-50-3) → benzene-1,4-diamine hydrochloride (624-18-0,55972-71-9)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; for 0.166667h;

DOI:10.1002/chem.201902556

Reference yield: 88.0%

para-dinitrobenzene (100-25-4) → benzene-1,4-diamine hydrochloride (624-18-0,55972-71-9)

Guidance literature:

With hydrogenchloride; titanium(III) chloride; In water; for 2h; Reagent/catalyst; Kinetics; Activation energy; Electrochemical reaction;

DOI:10.1007/s11172-021-3298-9

Reference yield: 82.0%

4-nitro-aniline (100-01-6,104810-17-5) → benzene-1,4-diamine hydrochloride (624-18-0,55972-71-9)

Guidance literature:

4-nitro-aniline; With hydrazine; In ethanol; at 50 - 78 ℃; for 0.75h; Green chemistry;

With hydrogenchloride; Green chemistry;

DOI:10.1134/S1070363218030064

upstream raw materials:

hydrogenchloride

4-(N-acetylamino)phenyl isothiocyanate

4-nitro-aniline

1,4-phenylenediamine

Downstream raw materials:

N,N,N',N'-tetramethyl-para-phenylenediamine

N,N,N',N'-tetraethyl-1,4-benzenediamine

N,N'''-p-phenylene-di-guanidine

5,5'-bis-(4-chloro-phenyl)-1,1'-p-phenylene-bis-biguanide; dihydrochloride

Refernces

• 1、 Abakumov, M. V.,Leonova, M. Yu.,Mikhalchenko, L. V.,Novikov, V. T.,Zaplavin, A. P.. "Reduction of dinitrobenzenes by electron-carrying catalysts in the electrosynthesis of diaminobenzenes". . p. 1927 - 1933. Retrieved 2021/11/05.
• 2、 Ignatovich, Zh. V.,Ermolinskaya,Katok, Ya. M.,Koroleva,Eremin,Agabekov. "Catalytic Activity of Nickel Nanoparticles in the Reaction of Reduction of Nitroarenes". . p. 410 - 417. Retrieved 2018/04/23.