5-Methyl-isothiazole

Base Information

• Chemical Name: 5-Methyl-isothiazole
• CAS No.: 693-97-0
• Molecular Formula: C₄H₅NS
• Molecular Weight: 99.1564
• Hs Code.: 2934999090
• Mol file: 693-97-0.mol

Synonyms:5-Methylisothiazole

Chemical Property of 5-Methyl-isothiazole

Chemical Property:

• Vapor Pressure: 6.25mmHg at 25°C
• Boiling Point: 145°C at 760 mmHg
• PKA: 4.62±0.20(Predicted)
• Flash Point: 39.4°C
• PSA: 41.13000
• Density: 1.121g/cm³
• LogP: 1.45150

Purity/Quality:

98% ^*data from raw suppliers

5-METHYL-ISOTHIAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Methyl-isothiazole

There total 3 articles about 5-Methyl-isothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-thiocyanato-but-2-enal (92600-02-7) → 5-methylisothiazole (693-97-0)

Guidance literature:

With ammonium thiocyanate; In acetone; for 1h; Heating;

Reference yield:

2-methylthiazole (3581-87-1,260998-77-4) → 5-methylisothiazole (693-97-0)

Guidance literature:

With trifluoroacetic acid; Ambient temperature; Irradiation;

DOI:10.1021/jo00064a033

Reference yield:

→ 5-methylisothiazole (693-97-0)

Guidance literature:

1-Buten u. 2-Buten, SO2, NH3, Katalysator (300-350grad);

upstream raw materials:

3-thiocyanato-but-2-enal

2-methylthiazole

Downstream raw materials:

isothiazole-5-carboxylic acid

5-methylthiazole

Refernces