3H-imidazo[4,5-f]quinolin-2-amine

Base Information Edit

Chemical Name:3H-imidazo[4,5-f]quinolin-2-amine
CAS No.:76180-97-7
Molecular Formula:C₁₀H₈N₄
Molecular Weight:184.2
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10227049
Nikkaji Number:J527.877E
Wikidata:Q83106674
Mol file:76180-97-7.mol

Synonyms:76180-97-7;3H-imidazo[4,5-f]quinolin-2-amine;2-Aminoimidazo(4,5-f)quinoline;2-Aminoimidazo[4,5-f]quinoline;1H-Imidazo(4,5-f)quinolin-2-amine;1H-IMIDAZO[4,5-F]QUINOLIN-2-AMINE;starbld0008881;NIOSH/NJ5906450;DTXSID10227049;BDA18097;2-Amino-3H-imidazo(4,5-f)quinoline;3H-Imidazo[4,5-f]quinolin-2-ylamine;3H-Imidazo(4,5-f)quinoline, 2-amino-;DISCONTINUED. Please see A611683.;LS-80490;FT-0661862;NJ59064500

Suppliers and Price of 3H-imidazo[4,5-f]quinolin-2-amine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3H-imidazo[4,5-f]quinolin-2-amine Edit

Chemical Property:

Vapor Pressure:6.09E-10mmHg at 25°C
Refractive Index:1.873
Boiling Point:495.1 °C at 760 mmHg
PKA:13.21±0.40(Predicted)
Flash Point:285.3 °C
PSA：68.32000
Density:1.476 g/cm³
LogP:1.62340
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:184.074896272
Heavy Atom Count:14
Complexity:220

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC3=C2N=C(N3)N)N=C1
Uses A metabolite of the carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), (A616500).

Technology Process of 3H-imidazo[4,5-f]quinolin-2-amine

There total 2 articles about 3H-imidazo[4,5-f]quinolin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: C₁₀H₈N₄

: 76180-97-7
2-amino-3H-imidazo<4,5-f>quinoline

Guidance literature:: In diphenylether; at 190 ℃;
DOI:10.1016/S0040-4039(97)00559-5

Reference yield:

: 42606-37-1
6-amino-5-nitroquinoline

: 76180-97-7
2-amino-3H-imidazo<4,5-f>quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: conc. HCl, Fe / 0.25 h

2: 35 mg / 4 h

With hydrogenchloride; iron;
DOI:10.1039/P19810002290