(+)-(S)-2,9-diisopropyl-1,2,3,4-tetrahydro-1,10-phenanthroline

Base Information

• Chemical Name: (+)-(S)-2,9-diisopropyl-1,2,3,4-tetrahydro-1,10-phenanthroline
• CAS No.: 1032154-71-4
• Molecular Formula: C₂₀H₂₈N₂
• Molecular Weight: 296.456
• Mol file: 1032154-71-4.mol

Synonyms:(+)-(S)-2,9-diisopropyl-1,2,3,4-tetrahydro-1,10-phenanthroline

Chemical Property of (+)-(S)-2,9-diisopropyl-1,2,3,4-tetrahydro-1,10-phenanthroline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-(S)-2,9-diisopropyl-1,2,3,4-tetrahydro-1,10-phenanthroline

There total 2 articles about (+)-(S)-2,9-diisopropyl-1,2,3,4-tetrahydro-1,10-phenanthroline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2,9-di-n-butyl-1,10-phenanthroline (85575-93-5) → (+)-(S)-2,9-diisopropyl-1,2,3,4-tetrahydro-1,10-phenanthroline (1032154-71-4)

Guidance literature:

2,9-di-n-butyl-1,10-phenanthroline; With Ru(trifluoromethanesulfonate)(N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine)(η6-cymene); hydrogen; In methanol; at 25 ℃; for 2h; under 38002.6 Torr; Inert atmosphere; Schlenk technique; Glovebox;

at 25 ℃; for 12h; enantioselective reaction;

DOI:10.1002/anie.201301830

Reference yield:

2,9-di-n-butyl-1,10-phenanthroline (85575-93-5) → (+)-(S)-2,9-diisopropyl-1,2,3,4-tetrahydro-1,10-phenanthroline (1032154-71-4) + (2R,9R)-2,9-di-n-butyl-1,2,3,4,7,8,9,10-octahydro-1,10-phenanthroline (1032154-63-4) + C20H32N2 (1062550-63-3)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; chiral 3,3'-bis(9-phenanthryl)-BINOL-derived phosphoric acid; In benzene; at 60 ℃; for 24h; Title compound not separated from byproducts.;

DOI:10.1055/s-2008-1032103

upstream raw materials:

2,9-di-n-butyl-1,10-phenanthroline

Refernces

• 1、 Wang, Tianli,Chen, Fei,Qin, Jie,He, Yan-Mei,Fan, Qing-Hua. "Asymmetric ruthenium-catalyzed hydrogenation of 2- and 2,9-substituted 1,10-phenanthrolines". supporting information. p. 7172 - 7176. Retrieved 2013/07/26.