N-acetyl-α-aminopropionaldehyde

Base Information

• Chemical Name: N-acetyl-α-aminopropionaldehyde
• CAS No.: 73323-67-8
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115.132
• Mol file: 73323-67-8.mol

Synonyms:N-acetyl-α-aminopropionaldehyde

Chemical Property of N-acetyl-α-aminopropionaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-acetyl-α-aminopropionaldehyde

There total 1 articles about N-acetyl-α-aminopropionaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetylaminoethylene (5202-78-8,28408-65-3) + carbon monoxide (201230-82-2) → N-acetyl-α-aminopropionaldehyde (73323-67-8) + N-acetyl-3-aminopropanaldehyde (73323-68-9)

Guidance literature:

With hydrogen; carbonylhydridetris(triphenylphosphine)rhodium(I); In benzene; at 40 - 45 ℃; for 40h; under 25857.4 Torr; Yield given. Title compound not separated from byproducts;

DOI:10.1021/jo01299a022

Reference yield: 35.0%

2,4,5,6-tetraaminopyrimidine (1004-74-6) + N-acetyl-α-aminopropionaldehyde (73323-67-8) → 2,4-diamino-6-methylpteridine (708-74-7)

Guidance literature:

With triethylamine; at 20 ℃; for 240h;

DOI:10.1007/BF01094658

Reference yield: 30.0%

2,5,6-triamino-3,4-dihydro-4-pyrimidinone (1004-75-7) + N-acetyl-α-aminopropionaldehyde (73323-67-8) → 2-amino-6-methylpteridin-4(1H)-one (708-75-8)

Guidance literature:

With triethylamine; In water; N,N-dimethyl-formamide; at 20 ℃; for 120h; Product distribution; various substituted carbonyl compounds, regioselectivity;

DOI:10.1007/BF01094658

upstream raw materials:

acetylaminoethylene

carbon monoxide

Downstream raw materials:

2-amino-6-methylpteridin-4(1H)-one

2,4-diamino-6-methylpteridine

(S)-acetamidoalanine

(R)-2-(acetylamino)propanoic acid

Refernces