Diethylene glycol diacetate

Base Information

• Chemical Name: Diethylene glycol diacetate
• CAS No.: 628-68-2
• Molecular Formula: C8H14 O5
• Molecular Weight: 190.196
• Hs Code.: 2915.39
• European Community (EC) Number: 211-049-4
• NSC Number: 6310
• UNII: 9OA65529VT
• DSSTox Substance ID: DTXSID90879242
• Nikkaji Number: J36.586F
• Wikidata: Q27159547
• Mol file: 628-68-2.mol

Synonyms:diethylene glycol diacetate

Chemical Property of Diethylene glycol diacetate

Chemical Property:

• Appearance/Colour: clear liquid
• Vapor Pressure: 0.0249mmHg at 25°C
• Melting Point: 18 - 20 C
• Refractive Index: 1.430 - 1.432
• Flash Point: 110 ºC
• PSA: 61.83000
• Density: 1.101
• LogP: 0.12920
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 190.08412354
• Heavy Atom Count: 13
• Complexity: 148

Purity/Quality:

99.9% ^*data from raw suppliers

Diethylene Glycol Diacetate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=O)OCCOCCOC(=O)C

Technology Process of Diethylene glycol diacetate

There total 15 articles about Diethylene glycol diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

acetic anhydride (108-24-7) + diethylene glycol (111-46-6) → diethyleneglycol diacetate (628-68-2,27252-83-1)

Guidance literature:

With In(OSO₂CF₃)3; In acetonitrile; at 20 ℃;

DOI:10.1055/s-1999-2941

Reference yield: 90.0%

ethyl acetate (141-78-6) + diethylene glycol (111-46-6) → diethyleneglycol diacetate (628-68-2,27252-83-1)

Guidance literature:

With 8Na⁽¹⁺⁾*12C₄H₁₀NO^(1-)*2HO^(1-)*2Nd⁽³⁺⁾; In hexane; at 60 ℃; for 16h; Molecular sieve; Inert atmosphere; Schlenk technique;

DOI:10.1021/jo5016536

Reference yield: 82.0%

Acetyl bromide (506-96-7) + [2-(2-Benzyloxy-ethoxy)-ethoxy]-tert-butyl-dimethyl-silane → diethyleneglycol diacetate (628-68-2,27252-83-1)

Guidance literature:

With tin(II) bromide; In dichloromethane; for 0.333333h; Ambient temperature;

DOI:10.1016/S0040-4039(00)73040-1

upstream raw materials:

oxirane

acetic anhydride

acetic acid

diethylene glycol

Downstream raw materials:

1-(2-acetoxy-ethoxy)-2-benzoyloxy-ethane

Refernces

• 1、 Zeng, Ruijie,Sheng, Hongting,Zhang, Yongcang,Feng, Yan,Chen, Zhi,Wang, Junfeng,Chen, Man,Zhu, Manzhou,Guo, Qingxiang. "Heterobimetallic dinuclear lanthanide alkoxide complexes as acid-base difunctional catalysts for transesterification". . p. 9246 - 9252. Retrieved 2014/12/11.
• 2、 -. "Synthesis of Sterically Hindered Secondary Aminoether Alcohols". Page/Page column 6. . Retrieved 2010/11/28.