3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride

Base Information

• Chemical Name: 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride
• CAS No.: 1319716-00-1
• Molecular Formula: C₃₇H₄₁ClO₈S
• Molecular Weight: 681.247
• Mol file: 1319716-00-1.mol

Synonyms:3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride

Chemical Property of 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride

There total 1 articles about 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranose (223582-33-0) → 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride (1319716-00-1)

Guidance literature:

With pyridine; thionyl chloride; In dichloromethane; at 20 ℃; for 0.166667h;

DOI:10.1016/j.carres.2011.04.027

Reference yield: 59.0%

3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride (1319716-00-1) + 4-methoxyphenyl 2,6-di-O-benzoyl-β-D-galactopyranosyl-(1->4)-2,6-di-O-benzoyl-3-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-β-D-glucopyranoside → 4-methoxyphenyl 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl-(1->3)-2,6-di-O-benzoyl-β-D-galactopyranosyl-(1->4)-2,6-di-O-benzoyl-3-O-(2,3,4-tri-O-benzyl-α-L-fucopyranosyl)-β-D-glucopyranoside

Guidance literature:

With silver trifluoromethanesulfonate; In dichloromethane; at 0 ℃; Molecular sieve;

DOI:10.1016/j.carres.2011.04.027

Reference yield: 28.0%

3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride (1319716-00-1) + methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl-(2->5)-3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside (1381871-30-2) → methyl 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl-(2->5)-3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl-(2->5)-3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside (1381871-31-3)

Guidance literature:

With silver trifluoromethanesulfonate; In dichloromethane; toluene; at 0 ℃; for 120h; Inert atmosphere; Molecular sieve;

DOI:10.1016/j.tet.2012.04.067

upstream raw materials:

3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranose

Downstream raw materials:

C₃₇H₄₀O₈S

2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-ethoxysulfonyl-D-glucohept-2-enitol

4-methoxyphenyl 2,3,6-tri-O-benzyl-4-O-(3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl)-β-D-glucopyranoside

methyl 2,3,6-tri-O-benzyl-4-O-(3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl)-β-D-glucopyranoside

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