Technology Process of C22H30N7O8P
There total 10 articles about C22H30N7O8P which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C10H14N6O4;
With
2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one;
at 0 ℃;
for 2.5h;
Inert atmosphere;
(S)-2-[(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one;
at 0 - 20 ℃;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h
2.1: ammonia / methanol / 3 h / 20 °C
3.1: 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 2.5 h / 0 °C / Inert atmosphere
3.2: 0 - 20 °C / Inert atmosphere
With
2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex; tetrabutyl ammonium fluoride; ammonia;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; methanol;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
2.1: 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 2.5 h / 0 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
With
2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex; triethylamine;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; dichloromethane;
![(S)-2-[(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester](/Databaselist/images/loading.webp)
