1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene

Base Information

• Chemical Name: 1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene
• CAS No.: 161436-20-0
• Molecular Formula: C₁₁H₁₃FO₂
• Molecular Weight: 196.221
• Nikkaji Number: J749.470J
• Mol file: 161436-20-0.mol

Synonyms:1,2-dimethoxy-4-(3-fluoro-2-propenyl)benzene

Chemical Property of 1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene

Chemical Property:

• Boiling Point: 258.073 °C at 760 mmHg
• Flash Point: 117.058 °C
• Density: 1.056 g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 196.08995782
• Heavy Atom Count: 14
• Complexity: 182

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)CC=CF)OC
• Isomeric SMILES: COC1=C(C=C(C=C1)C/C=C/F)OC

Technology Process of 1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene

There total 6 articles about 1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-Dimethoxy-4-<3-fluoro-3-(phenylsulfonyl)-2-propenyl>benzene → 1,2-dimethoxy-4-(2-propenyl)benzene (93-15-2) + Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene (161436-14-2,161436-20-0) + (E)-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene (161436-20-0) + Methylisoeugenol (93-16-3)

Guidance literature:

With disodium hydrogenphosphate; sodium amalgam; In tetrahydrofuran; methanol; at 25 ℃; for 0.333333h; Product distribution; various time, temp.;

DOI:10.1021/jo00105a019

Reference yield:

1,2-Dimethoxy-4-<3-fluoro-3-(phenylsulfonyl)-2-propenyl>benzene → 1,2-dimethoxy-4-(2-propenyl)benzene (93-15-2) + Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene (161436-14-2,161436-20-0) + (E)-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene (161436-20-0) + Methylisoeugenol (93-16-3)

Guidance literature:

With disodium hydrogenphosphate; sodium amalgam; In tetrahydrofuran; methanol; at 25 ℃; for 0.333333h; Product distribution; various time, temp.;

DOI:10.1021/jo00105a019

Reference yield:

Tributyl-[(E)-3-(3,4-dimethoxy-phenyl)-1-fluoro-propenyl]-phosphonium; chloride → Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene (161436-14-2,161436-20-0) + (E)-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene (161436-20-0)

Guidance literature:

With sodium hydroxide; In dichloromethane; at 35 ℃; for 1.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/jo00105a019

Refernces