Pefloxacin mesylate

Base Information

• Chemical Name: Pefloxacin mesylate
• CAS No.: 70458-95-6
• Molecular Formula: C17H20FN3O3^.CH4O3S
• Molecular Weight: 429.469
• Hs Code.: 2933599090
• European Community (EC) Number: 274-613-9,641-363-0
• NSC Number: 758944
• UNII: 5IAD0UV3FH
• DSSTox Substance ID: DTXSID8045935
• Wikidata: Q27121975
• NCI Thesaurus Code: C72825
• ChEMBL ID: CHEMBL1428564
• Mol file: 70458-95-6.mol

Synonyms:2589 R.B.;Abactal;Dihydrate, Pefloxacin Mesylate;Mesylate Dihydrate, Pefloxacin;Mesylate, Pefloxacin;Peflacine;Pefloxacin;Pefloxacin Mesylate;Pefloxacin Mesylate Dihydrate;Pefloxacin, Silver;Pefloxacine;R.B., 2589;Silver Pefloxacin

Chemical Property of Pefloxacin mesylate

Chemical Property:

• Vapor Pressure: 5.05E-12mmHg at 25°C
• Boiling Point: 529.1 °C at 760 mmHg
• Flash Point: 273.8 °C
• PSA: 128.53000
• Density: 1.32 g/cm3
• LogP: 2.19820
• Storage Temp.: Refrigerator
• Solubility.: Freely soluble in water, slightly soluble in ethanol (96 per cent), very slightly soluble in methylene chloride.
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 3
• Exact Mass: 429.13698483
• Heavy Atom Count: 29
• Complexity: 638

Purity/Quality:

99% ^*data from raw suppliers

Pefloxacin mesylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, C
• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O.CS(=O)(=O)O
• Recent ClinicalTrials: Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
• Recent EU Clinical Trials: A Phase 2, Open-Label, Multicenter, Efficacy, Safety, Tolerability, and Pharmacokinetic Study of ANF–Rho? in Patients with Chronic Neutropenia
• Description: Pefloxacin mesylate is a broad-spectrum, third generation quinolone antibacterial agent useful in the treatment of infections due to a variety of organisms, including methicillin-resistant S. aureus. A major metabolite of pefloxacin is norfloxacin.
• Uses: Pefloxacin mesylate is a synthetic chemotherapeutic agent and an antibacterial agent with IC50 of 6.7 nM. Pefloxacin is a fluorinated quinolone antibacterial; analog of Norfloxacin.

Technology Process of Pefloxacin mesylate

There total 1 articles about Pefloxacin mesylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Peflox (70458-95-6)

Guidance literature: