C₁₃H₁₂N₂O₂

Base Information

• Chemical Name: C₁₃H₁₂N₂O₂
• CAS No.: 1616603-26-9
• Molecular Formula: C₁₃H₁₂N₂O₂
• Molecular Weight: 228.25
• Mol file: 1616603-26-9.mol

Synonyms:C₁₃H₁₂N₂O₂

Chemical Property of C₁₃H₁₂N₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₁₂N₂O₂

There total 4 articles about C₁₃H₁₂N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(1-(hydroxyimino)but-3-en-1-yl)benzonitrile (1403477-81-5) + acetyl chloride (75-36-5) → C13H12N2O2 (1616603-26-9)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1039/c4cc03129f

Reference yield:

1-(p-cyanophenyl)-3-buten-1-ol (71787-53-6) → C13H12N2O2 (1616603-26-9)

Guidance literature:

Multi-step reaction with 3 steps

1: Jones reagent / diethyl ether / 0 - 20 °C

2: hydroxylamine hydrochloride; sodium acetate / water; ethanol / 20 °C

3: triethylamine / dichloromethane / 0 °C

With Jones reagent; hydroxylamine hydrochloride; sodium acetate; triethylamine; In diethyl ether; ethanol; dichloromethane; water;

DOI:10.1039/c4cc03129f

Reference yield:

4-but-3-enoylbenzonitrile → C13H12N2O2 (1616603-26-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / water; ethanol / 20 °C

2: triethylamine / dichloromethane / 0 °C

With hydroxylamine hydrochloride; sodium acetate; triethylamine; In ethanol; dichloromethane; water;

DOI:10.1039/c4cc03129f

upstream raw materials:

4-cyanobenzaldehyde

1-(p-cyanophenyl)-3-buten-1-ol

4-(1-(hydroxyimino)but-3-en-1-yl)benzonitrile

acetyl chloride

Downstream raw materials:

4-(1H-pyrrol-2-yl)benzonitrile

Refernces