Glycyl-L-phenylalanine 2-naphthylamide

Base Information

• Chemical Name: Glycyl-L-phenylalanine 2-naphthylamide
• CAS No.: 21438-66-4
• Molecular Formula: C21H21 N3 O2
• Molecular Weight: 347.417
• Hs Code.: 2924299090
• European Community (EC) Number: 620-677-1
• DSSTox Substance ID: DTXSID50944021
• Nikkaji Number: J1.175.466J
• Wikidata: Q27162699
• ChEMBL ID: CHEMBL22827
• Mol file: 21438-66-4.mol

Synonyms:Gly-Phe-naphthylamide;glycyl-L-phenylalanine 2-naphthylamide;glycyl-L-phenylalanine-beta-naphthylamide;glycylphenylalanine 2-naphthylamide

Chemical Property of Glycyl-L-phenylalanine 2-naphthylamide

Chemical Property:

• Vapor Pressure: 5.04E-19mmHg at 25°C
• Boiling Point: 692.4°Cat760mmHg
• Flash Point: 372.6°C
• PSA: 84.22000
• Density: 1.254g/cm³
• LogP: 3.62870
• Storage Temp.: −20°C
• Solubility.: Soluble in 100mg in 200µl DMSO.
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 347.16337692
• Heavy Atom Count: 26
• Complexity: 476

Purity/Quality:

99%, ^*data from raw suppliers

Gly-Phe beta-naphthylamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 40
• Safety Statements: 22-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(C(=O)NC2=CC3=CC=CC=C3C=C2)NC(=O)CN
• Isomeric SMILES: C1=CC=C(C=C1)C[C@@H](C(=O)NC2=CC3=CC=CC=C3C=C2)NC(=O)CN
• Uses: Gly-Phe beta-naphthylamide is used to accumulate inside lysosomes leading to their destruction. Studies report that Gly-Phe-β-naphthylamide significantly inhibits the activation of caspase-8, and has also been used to study recombinant cathepsin C.