N-Octadecylmaleamic acid

Base Information

• Chemical Name: N-Octadecylmaleamic acid
• CAS No.: 3077-27-8
• Deprecated CAS: 2173381-96-7
• Molecular Formula: C22H41 N O3
• Molecular Weight: 367.572
• Hs Code.: 2924199090
• European Community (EC) Number: 221-361-2,637-420-4
• Nikkaji Number: J2.270.107J
• Mol file: 3077-27-8.mol

Synonyms:N-Octadecylmaleamic acid;EINECS 221-361-2;AI3-09140;2-Butenoic acid, 4-(octadecylamino)-4-oxo-, (Z)-;4-(Octadecylamino)-4-oxoisocrotonic acid;fumaric acid-N-octadecylamide;SCHEMBL1289328;AKOS024431605;4-(Octadecylamino)-4-oxo-2-butenoic acid

Chemical Property of N-Octadecylmaleamic acid

Chemical Property:

• Vapor Pressure: 1.01E-12mmHg at 25°C
• Boiling Point: 531.7°Cat760mmHg
• Flash Point: 275.4°C
• PSA: 69.89000
• Density: 0.952g/cm³
• LogP: 6.84520
• Water Solubility.: 5.9mg/L at 25℃
• XLogP3: 8.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 19
• Exact Mass: 367.30864417
• Heavy Atom Count: 26
• Complexity: 366

Purity/Quality:

99.9% ^*data from raw suppliers

N-OCTADECYLMALEAMIC ACID AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCCNC(=O)C=CC(=O)O
• Isomeric SMILES: CCCCCCCCCCCCCCCCCCNC(=O)/C=C/C(=O)O

Technology Process of N-Octadecylmaleamic acid

There total 2 articles about N-Octadecylmaleamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

maleic anhydride (108-31-6) + 1-aminooctadecane (124-30-1) → (N-octadecyl)maleamic acid (3077-27-8)

Guidance literature:

With toluene;

DOI:10.1021/jo01083a626

Reference yield:

→ (N-octadecyl)maleamic acid (3077-27-8)

Guidance literature:

Maleinsaeureanhydrid, n-Octadecylamin;

Reference yield:

(N-octadecyl)maleamic acid (3077-27-8) → N-n-octadecylmaleimide (17450-30-5)

Guidance literature:

With sodium acetate; acetic anhydride; for 0.5h; Heating / reflux;

upstream raw materials:

maleic anhydride

1-aminooctadecane

Downstream raw materials:

N-n-octadecylmaleimide

Refernces

• 1、 -. "Drug delivery system". Page/Page column 6-7. . Retrieved 2008/06/13.