4-Amino-2-methyl-5-pyrimidinemethanesulfonic acid

Base Information

• Chemical Name: 4-Amino-2-methyl-5-pyrimidinemethanesulfonic acid
• CAS No.: 2908-73-8
• Molecular Formula: C6H9N3O3S
• Molecular Weight: 203.222
• Mol file: 2908-73-8.mol

Synonyms:4-Amino-2-methyl-5-pyrimidinemethanesulfonic acid

Chemical Property of 4-Amino-2-methyl-5-pyrimidinemethanesulfonic acid

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.571g/cm³
• XLogP3: -1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 203.03646233
• Heavy Atom Count: 13
• Complexity: 248

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=[NH+]C=C(C(=N1)N)CS(=O)(=O)[O-]

Technology Process of 4-Amino-2-methyl-5-pyrimidinemethanesulfonic acid

There total 5 articles about 4-Amino-2-methyl-5-pyrimidinemethanesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiamin chloride hydrochloride (59-43-8) → 5-hydroxyethyl-4-methylthiazole (137-00-8,8042-97-5) + (4-amino-2-methylpyrimidin-5-yl)methanesulfonic acid (2908-73-8)

Guidance literature:

With calcium sulfite; acetate buffer; In water; for 21h; Mechanism; Ambient temperature; pH 5.4;

DOI:10.1021/jo00324a040

Reference yield:

Aneurin (70-16-6) + sodium hydrogensulfite → 5-hydroxyethyl-4-methylthiazole (137-00-8,8042-97-5) + (4-amino-2-methylpyrimidin-5-yl)methanesulfonic acid (2908-73-8)

Guidance literature:

DOI:10.1021/ja01306a044

Reference yield:

vitamin B1 (59-43-8) → 5-hydroxyethyl-4-methylthiazole (137-00-8,8042-97-5) + (4-amino-2-methylpyrimidin-5-yl)methanesulfonic acid (2908-73-8)

Guidance literature:

With potassium hexacyanoferrate(III); sulfite oxidase; Kinetics; Electrochemical reaction; Enzymatic reaction;

DOI:10.1002/smll.201903153

upstream raw materials:

pyridine

Aneurin

aniline

thiamin chloride hydrochloride

Refernces

• 1、 Zoltewicz, John A.,Uray, Georg. "Nature of the Reaction of Thiamin in the Presence of Low Concentrations of Sulfite Ion. Competitive Trapping". . p. 2398 - 2400. Retrieved 2007/10/02.