4-Chloro-N,N-diethylbenzaMide, 97%

Base Information

• Chemical Name: 4-Chloro-N,N-diethylbenzaMide, 97%
• CAS No.: 7461-38-3
• Molecular Formula: C11H14ClNO
• Molecular Weight: 211.691
• Mol file: 7461-38-3.mol

Synonyms:4-chloro-N,N-diethyl-benzamide;p-ClC6H4CONEt2;N,N-diethyl-4-chlorobenzamide;

Chemical Property of 4-Chloro-N,N-diethylbenzaMide, 97%

Chemical Property:

• Vapor Pressure: 0.000158mmHg at 25°C
• Boiling Point: 331.2°Cat760mmHg
• Flash Point: 154.1°C
• PSA: 20.31000
• Density: 1.115g/cm³
• LogP: 2.82200

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-N,N-diethylbenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Chloro-N,N-diethylbenzaMide, 97%

There total 23 articles about 4-Chloro-N,N-diethylbenzaMide, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-chloro-benzoyl chloride (122-01-0) + diethylamine (109-89-7) → 4-chloro-N,N-diethyl-benzamide (7461-38-3)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 6h;

DOI:10.1021/acs.orglett.0c00827

Reference yield: 94.0%

4-chlorotrichloromethylbenzene (5216-25-1) + triethylamine (121-44-8) → 4-chloro-N,N-diethyl-benzamide (7461-38-3)

Guidance literature:

With B₁₂ complex immobilized on rhodium(III) modified anatase TiO₂; air; In acetonitrile; at 20 ℃; for 3h; Irradiation;

DOI:10.1016/j.jorganchem.2019.121058

Reference yield: 94.0%

diethylamine (109-89-7) + para-chlorobenzoic acid (74-11-3) → 4-chloro-N,N-diethyl-benzamide (7461-38-3)

Guidance literature:

With fluorosulfonyl fluoride; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 5h;

DOI:10.1039/c9ob00699k

upstream raw materials:

4-chloro-benzoyl chloride

diethylamine

p-Chlorobenzoylthiochlorosulfit

diethylammonium diethyldithiocarbamate

Downstream raw materials:

4-chlorobenzaldehyde

N,N-diethyl p-butyl-benzamide

(S)-2-methyl-1,2,3,4-tetrahydroquinoline

(R)-1,2,3,4-tetrahydroquinaldine

Refernces

• 1、 Habibi, Hassan,Mansourinejhad, Sanam,Saberi, Dariush,Shadi, Ahmad. "One-pot synthesis of a highly disperse core-shell CuO-alginate nanocomposite and the investigation of its antibacterial and catalytic properties". . p. 199 - 211. Retrieved 2021/12/30.
• 2、 Singha, Krishnadipti,Ghosh, Subhash Chandra,Panda, Asit Baran. "Visible Light-Driven Efficient Synthesis of Amides from Alcohols using Cu?N?TiO2 Heterogeneous Photocatalyst". . p. 657 - 662. Retrieved 2021/02/02.