2-iodo-5-diethyiaminophenyl acetate

Base Information

• Chemical Name: 2-iodo-5-diethyiaminophenyl acetate
• CAS No.: 342890-09-9
• Molecular Formula: C₁₂H₁₆INO₂
• Molecular Weight: 333.169
• Mol file: 342890-09-9.mol

Synonyms:2-iodo-5-diethyiaminophenyl acetate

Chemical Property of 2-iodo-5-diethyiaminophenyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-iodo-5-diethyiaminophenyl acetate

There total 2 articles about 2-iodo-5-diethyiaminophenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-(diethylamino)phenyl acetate (18997-95-0) → 2-iodo-5-diethyiaminophenyl acetate (342890-09-9)

Guidance literature:

With iodine; thallium(I) acetate; In dichloromethane;

DOI:10.1021/ja002370t

Reference yield:

3-diethylaminophenol (91-68-9) → 2-iodo-5-diethyiaminophenyl acetate (342890-09-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / aq. NaOH / 2 h

2: 78 percent / I₂; thallium(I) acetate / CH₂Cl₂

With sodium hydroxide; iodine; thallium(I) acetate; In dichloromethane;

DOI:10.1021/ja002370t

Reference yield: 93.0%

2-iodo-5-diethyiaminophenyl acetate (342890-09-9) + trimethylsilylacetylene (1066-54-2) → 3-diethylamino-6-(trimethylsilyl)ethynylphenyl acetate. (342890-27-1)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine;

DOI:10.1021/ja002370t

upstream raw materials:

3-(diethylamino)phenyl acetate

3-diethylaminophenol

Downstream raw materials:

3-diethylamino-6-(trimethylsilyl)ethynylphenyl acetate.

3-diethylamino-6-ethynylphenyl acetate

Refernces