N,N-Diacetylchitobiose

Base Information

• Chemical Name: N,N-Diacetylchitobiose
• CAS No.: 35061-50-8
• Molecular Formula: C16H28 N2 O11
• Molecular Weight: 424.405
• Hs Code.: 29329990
• European Community (EC) Number: 636-876-1
• Mol file: 35061-50-8.mol

Synonyms:(GlcNAc)2;bis(N-acetyl)chitobiose;di-N-acetylchitobiose;N,N'-diacetylchitobiose;N,N'-diacetylchitobioside;N,N-diacetylchitobiose

Chemical Property of N,N-Diacetylchitobiose

Chemical Property:

• Appearance/Colour: White Solid
• Melting Point: 245-247 °C(lit.)
• Boiling Point: 927.7 °C at 760 mmHg
• PKA: 12.85±0.20(Predicted)
• Flash Point: 514.8 °C
• PSA: 207.27000
• Density: 1.5 g/cm³
• LogP: -4.32780
• Storage Temp.: −20°C
• Solubility.: H2O: 50 mg/mL, clear, colorless
• XLogP3: -4.7
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 6
• Exact Mass: 424.16930971
• Heavy Atom Count: 29
• Complexity: 579

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N''-Diacetylchitobiose ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=O)NC1C(C(C(OC1O)CO)OC2C(C(C(C(O2)CO)O)O)NC(=O)C)O
• Uses: An inhibitor of lysozyme, reverses myocardial depression and lessens norepinephrine requirements in Escherichia coli sepsis in dogs. lectin inhibitor, immunopotentiator Diacetylchitobiose/Chitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is used as an alternative source of N-acetylglucosamine by some bacteria. It is used in fermentation research to study, differentiate and characterize chitobiose transporter systems and enzymes such as β-N-acetylglucosaminidase(s) and chitobiose phosphorylase(s).

Technology Process of N,N-Diacetylchitobiose

There total 7 articles about N,N-Diacetylchitobiose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

chitin (1398-61-4) → N,N’-diacetylchitobiose (35061-50-8)

Guidance literature:

chitin; With hydrogenchloride; In water; at 20 ℃;

With recombinant chitinase A from Serratia marcescens; sodium acetate; at 37 ℃; for 240h; pH=5.7; aq. buffer; Enzymatic reaction;

DOI:10.1002/jccs.200900103

Reference yield:

chitin (1398-61-4) → 2-acetamido-2-deoxy-D-glucose (7512-17-6,282727-46-2,478518-83-1,127959-06-2,78393-48-3) + N,N’-diacetylchitobiose (35061-50-8)

Guidance literature:

chitin; With hydrogenchloride; In water; at 20 ℃;

With recombinant chitinase A from Serratia marcescens; pH=6 - 8; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1002/jccs.200900103

Reference yield:

colloidal shrimp shell chitin → 2-acetamido-2-deoxy-D-glucose (7512-17-6,282727-46-2,478518-83-1,127959-06-2,78393-48-3) + N,N’-diacetylchitobiose (35061-50-8) + tri(N-acetyl)chitotriose (38864-21-0)

Guidance literature:

With chitinase from Humicola grisea ITCC 10,360.16; In aq. buffer; at 70 ℃; pH=3.0; Kinetics; Enzymatic reaction;

DOI:10.1016/j.ijbiomac.2018.05.125

upstream raw materials:

chitin

Refernces

• 1、 Kumar, Manish,Brar, Amandeep,Vivekanand,Pareek, Nidhi. "Process optimization, purification and characterization of a novel acidic, thermostable chitinase from Humicola grisea". . p. 931 - 938. Retrieved 2018/05/29.