tetrahydrothiophen-2-yl benzoate

Base Information

• Chemical Name: tetrahydrothiophen-2-yl benzoate
• CAS No.: 59661-77-7
• Molecular Formula: C₁₁H₁₂O₂S
• Molecular Weight: 208.281
• Mol file: 59661-77-7.mol

Synonyms:tetrahydrothiophen-2-yl benzoate

Chemical Property of tetrahydrothiophen-2-yl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of tetrahydrothiophen-2-yl benzoate

There total 4 articles about tetrahydrothiophen-2-yl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

thiophene (110-01-0) + benzoic acid (65-85-0,8013-63-6) → tetrahydrothiophen-2-yl benzoate (59661-77-7)

Guidance literature:

With tetrabutylammonium tetrafluoroborate; In methanol; acetonitrile; at 20 ℃; for 6h; Inert atmosphere; Electrochemical reaction;

DOI:10.1021/jacs.1c00288

Reference yield: 46.0%

thiophene (110-01-0) + tert-Butyl peroxybenzoate (614-45-9) → tetrahydrothiophen-2-yl benzoate (59661-77-7)

Guidance literature:

With copper-iron mixed oxide; In dichloromethane; acetonitrile; at 140 ℃; for 24h; Sealed tube;

DOI:10.1021/acs.joc.5b01043

Reference yield:

thiophene (110-01-0) + dibenzoyl peroxide (94-36-0) → tetrahydrothiophen-2-yl benzoate (59661-77-7)

Guidance literature:

With chloroform;

upstream raw materials:

thiophene

dibenzoyl peroxide

tert-Butyl peroxybenzoate

benzoic acid

Refernces

• 1、 García-Cabeza, Ana Leticia,Marín-Barrios, Rubén,Moreno-Dorado, F. Javier,Ortega, María J.,Vidal, Hilario,Gatica, José M.,Massanet, Guillermo M.,Guerra, Francisco M.. "Acyloxylation of 1,4-Dioxanes and 1,4-Dithianes Catalyzed by a Copper-Iron Mixed Oxide". . p. 6814 - 6821. Retrieved 2015/10/06.