N,2-dimethyl-5-nitroformanilide

Base Information

• Chemical Name: N,2-dimethyl-5-nitroformanilide
• CAS No.: 32417-73-5
• Molecular Formula: C₉H₁₀N₂O₃
• Molecular Weight: 194.19
• Mol file: 32417-73-5.mol

Synonyms:N,2-dimethyl-5-nitroformanilide

Chemical Property of N,2-dimethyl-5-nitroformanilide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,2-dimethyl-5-nitroformanilide

There total 3 articles about N,2-dimethyl-5-nitroformanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + N-methyl-2-methyl-4-nitroaniline (10439-77-7) → N,2-dimethyl-5-nitroformanilide (32417-73-5)

Guidance literature:

With sodium (phenyltrihydroxyborate); phenylsilane; In diethylene glycol dimethyl ether; at 100 ℃; for 12h; under 1875.19 Torr; Sealed tube; Glovebox; Autoclave;

DOI:10.1039/d0gc01741h

Reference yield:

N-formyl-2-methyl-4-nitroaniline (26198-11-8) + methyl iodide (74-88-4) → N,2-dimethyl-5-nitroformanilide (32417-73-5)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 5 min, 2.) DMF, methylene dichloride, 1 h, RT;

Reference yield:

→ N,2-dimethyl-5-nitroformanilide (32417-73-5)

Guidance literature:

2-Methyl-4-nitro-dimethylanilin, Ozonolyse, Abtrennung durch Chromatographie;

DOI:10.1039/j39710001369

upstream raw materials:

N-formyl-2-methyl-4-nitroaniline

methyl iodide

carbon dioxide

N-methyl-2-methyl-4-nitroaniline

Downstream raw materials:

N-methyl-2-methyl-4-nitroaniline

Refernces

• 1、 Collins, David J.,Drygala, Peter F.,Swan, John M.. "Organophosphorus Compounds. XX. Approaches to the Synthesis of 2,3-Dihydro-1H-1.2-benzazaphospholes Involving C-C and C-P Ring Closure". . p. 1009 - 1021. Retrieved 2007/10/02.