methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate

Base Information

• Chemical Name: methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate
• CAS No.: 20365-71-3
• Molecular Formula: C₁₁H₁₂O₂S₂
• Molecular Weight: 240.347
• Mol file: 20365-71-3.mol

Synonyms:methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate

Chemical Property of methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate

There total 3 articles about methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

(S,S)-dimethyl trithiocarbonate (2314-48-9) + 1-(4-methoxyphenyl)ethanone (100-06-1) → methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate (20365-71-3)

Guidance literature:

1-(4-methoxyphenyl)ethanone; With sodium hydride; In hexane; N,N-dimethyl-formamide; for 1h; Cooling with ice; Inert atmosphere;

(S,S)-dimethyl trithiocarbonate; at 20 ℃; for 8h;

DOI:10.1039/c4dt03816a

Reference yield: 21.7%

carbon disulfide (75-15-0,12122-00-8) + 1-(4-methoxyphenyl)ethanone (100-06-1) + methyl iodide (74-88-4) → methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate (20365-71-3)

Guidance literature:

carbon disulfide; 1-(4-methoxyphenyl)ethanone; With potassium tert-butylate; In diethyl ether; at 0 ℃; for 1.5h; Inert atmosphere;

methyl iodide; In diethyl ether; at 0 ℃; for 1.5h; Inert atmosphere;

DOI:10.1016/j.jorganchem.2014.07.023

Reference yield:

→ methyl 3-hydroxy-3-(p-methoxyphenyl)-2-propenedithiolate (20365-71-3)

Guidance literature:

3-(4-Methoxy-phenyl)-3-oxo-propandithiosaeure, durch Methylierung;

upstream raw materials:

carbon disulfide

1-(4-methoxyphenyl)ethanone

methyl iodide

(S,S)-dimethyl trithiocarbonate

Downstream raw materials:

3-(4-methoxybenzoyl)-2H-chromene-2-thione

3-(4-methoxybenzoyl)-2H-1-benzopyran-2-one

3-(4-methoxybenzoyl)-8-methoxy-2H-chromene-2-thione

8-methoxy-3-(4-methoxy-benzoyl)-coumarin

Refernces

• 1、 Rajput, Gunjan,Yadav, Manoj Kumar,Drew, Michael G. B.,Singh, Nanhai. "Influence of the ligand frameworks on the coordination environment and properties of new phenylmercury(II) β-oxodithioester complexes". . p. 5909 - 5916. Retrieved 2015.
• 2、 Kumari, Kavita,Kumar, Saurabh,Singh, Krishna Nand,Drew, Michael G. B.,Singh, Nanhai. "Synthesis and characterization of new square planar heteroleptic cationic complexes [Ni(ii) β-oxodithioester-dppe]+; Their use as a catalyst for Chan-Lam coupling". . p. 12143 - 12153. Retrieved 2020/07/30.