Technology Process of 17β-toluenesulfonyloxy-estra-1,3,5(10)-trien-3-ol
There total 8 articles about 17β-toluenesulfonyloxy-estra-1,3,5(10)-trien-3-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; palladium(II) hydroxide; acetic acid;
In
methanol; ethyl acetate;
for 16h;
DOI:10.1016/j.bmc.2011.12.036
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / tetrahydrofuran; ethanol / 1 h / 0 °C
2: pyridine / 0 - 20 °C
3: hydrogen; palladium(II) hydroxide; acetic acid / methanol; ethyl acetate / 16 h
With
pyridine; sodium tetrahydroborate; hydrogen; palladium(II) hydroxide; acetic acid;
In
tetrahydrofuran; methanol; ethanol; ethyl acetate;
DOI:10.1016/j.bmc.2011.12.036
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetone / 1 h
1.2: 4 h / Reflux
2.1: sodium tetrahydroborate / tetrahydrofuran; ethanol / 1 h / 0 °C
3.1: pyridine / 0 - 20 °C
4.1: hydrogen; palladium(II) hydroxide; acetic acid / methanol; ethyl acetate / 16 h
With
pyridine; sodium tetrahydroborate; hydrogen; palladium(II) hydroxide; potassium carbonate; acetic acid;
In
tetrahydrofuran; methanol; ethanol; ethyl acetate; acetone;
DOI:10.1016/j.bmc.2011.12.036
