6-benzyloxy-1-naphthoic acid benzyl ester

Base Information

• Chemical Name: 6-benzyloxy-1-naphthoic acid benzyl ester
• CAS No.: 865360-09-4
• Molecular Formula: C₂₅H₂₀O₃
• Molecular Weight: 368.432
• Mol file: 865360-09-4.mol

Synonyms:6-benzyloxy-1-naphthoic acid benzyl ester

Chemical Property of 6-benzyloxy-1-naphthoic acid benzyl ester

Chemical Property:

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Technology Process of 6-benzyloxy-1-naphthoic acid benzyl ester

There total 1 articles about 6-benzyloxy-1-naphthoic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

6-hydroxy-1-naphthoic acid (2437-17-4) + benzyl bromide (100-39-0) → 6-benzyloxy-1-naphthoic acid benzyl ester (865360-09-4)

Guidance literature:

With potassium hydroxide; In N,N-dimethyl-formamide; at 100 ℃; for 2h;

DOI:10.1021/jm0502743

Reference yield:

6-benzyloxy-1-naphthoic acid benzyl ester (865360-09-4) → 6-(benzyloxy)-1-naphthoic acid

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; for 32h; Heating;

DOI:10.1021/jm0502743

Reference yield:

6-benzyloxy-1-naphthoic acid benzyl ester (865360-09-4) → 6-benzyloxy-1-naphthoic acid chloride

Guidance literature:

With thionyl chloride;

DOI:10.1021/jm0502743

upstream raw materials:

6-hydroxy-1-naphthoic acid

benzyl bromide

Downstream raw materials:

3-(6-benzyloxy-1-naphthoyl)-1-(N-methylpiperidin-2-ylmethyl)indole

Refernces