Technology Process of (+/-)-(1RS,2SR)-5,5-ethylenedithio-2-<2-(2-methoxyphenyl)ethyl>-1,3,3-trimethylcyclohexanecarbaldehyde
There total 4 articles about (+/-)-(1RS,2SR)-5,5-ethylenedithio-2-<2-(2-methoxyphenyl)ethyl>-1,3,3-trimethylcyclohexanecarbaldehyde which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 71 percent / triethylaluminium / tetrahydrofuran / 22 h / Ambient temperature
2: 92 percent / boron trifluoride-diethyl ether / CH2Cl2 / 5 h / Ambient temperature
3: 1.) DIBAL; 2.) aq. HCl / 1.) DME, reflux, 2 h; 2.) reflux, 2 h.
With
hydrogenchloride; boron trifluoride diethyl etherate; triethylaluminum; diisobutylaluminium hydride;
In
tetrahydrofuran; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) copper(I)bromide; 2.) aq. HCl / 1.) diethyl ether, THF, 0 deg C; rt, 0.5 h; 2.)THF, reflux, 2 h.
2: 71 percent / triethylaluminium / tetrahydrofuran / 22 h / Ambient temperature
3: 92 percent / boron trifluoride-diethyl ether / CH2Cl2 / 5 h / Ambient temperature
4: 1.) DIBAL; 2.) aq. HCl / 1.) DME, reflux, 2 h; 2.) reflux, 2 h.
With
hydrogenchloride; boron trifluoride diethyl etherate; triethylaluminum; diisobutylaluminium hydride; copper(I) bromide;
In
tetrahydrofuran; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 92 percent / boron trifluoride-diethyl ether / CH2Cl2 / 5 h / Ambient temperature
2: 1.) DIBAL; 2.) aq. HCl / 1.) DME, reflux, 2 h; 2.) reflux, 2 h.
With
hydrogenchloride; boron trifluoride diethyl etherate; diisobutylaluminium hydride;
In
dichloromethane;
