D(+)-O,O-dibenzoyl tartarate of zopiclone

Base Information

• Chemical Name: D(+)-O,O-dibenzoyl tartarate of zopiclone
• CAS No.: 1020156-02-8
• Molecular Formula: C₁₇H₁₇ClN₆O₃*C₁₈H₁₄O₈
• Molecular Weight: 747.118
• Mol file: 1020156-02-8.mol

Synonyms:D(+)-O,O-dibenzoyl tartarate of zopiclone

Chemical Property of D(+)-O,O-dibenzoyl tartarate of zopiclone

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of D(+)-O,O-dibenzoyl tartarate of zopiclone

There total 1 articles about D(+)-O,O-dibenzoyl tartarate of zopiclone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.63%

O,O'-dibenzoyl-D-tartaric acid (17026-42-5) + zopiclon (43200-80-2) → D(+)-O,O-dibenzoyl tartarate of zopiclone (1020156-02-8)

Guidance literature:

In water; acetonitrile; at 25 - 35 ℃; for 7h;

Reference yield: 44.85%

D(+)-O,O-dibenzoyl tartarate of zopiclone (1020156-02-8) → (R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate D-(+)-O,O'-dibenzoyltartaric acid salt (144025-94-5) + eszopiclone dibenzoyl-D-tartrate (144025-93-4)

Guidance literature:

D(+)-O,O-dibenzoyl tartarate of zopiclone; In dichloromethane; Heating / reflux;

In dichloromethane; acetonitrile; at 50 - 55 ℃; for 0.333333h; Heating / reflux;

In dichloromethane; acetonitrile; Purification / work up; Heating / reflux;

Reference yield:

D(+)-O,O-dibenzoyl tartarate of zopiclone (1020156-02-8) → (-)-Zopiclone (138680-08-7)

Guidance literature:

D(+)-O,O-dibenzoyl tartarate of zopiclone; With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃; for 1h;

In butanone; for 0.5h; Reflux;

upstream raw materials:

O,O'-dibenzoyl-D-tartaric acid

zopiclon

Downstream raw materials:

(R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate D-(+)-O,O'-dibenzoyltartaric acid salt

eszopiclone dibenzoyl-D-tartrate

(-)-Zopiclone

eszopiclone

Refernces