5α-androst-1-en-3-one-17β-yl benzoate

Base Information

• Chemical Name: 5α-androst-1-en-3-one-17β-yl benzoate
• CAS No.: 1971-67-1
• Molecular Formula: C₂₆H₃₂O₃
• Molecular Weight: 392.538
• Mol file: 1971-67-1.mol

Synonyms:5α-androst-1-en-3-one-17β-yl benzoate

Chemical Property of 5α-androst-1-en-3-one-17β-yl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5α-androst-1-en-3-one-17β-yl benzoate

There total 11 articles about 5α-androst-1-en-3-one-17β-yl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dl-Δ1-5β-androsten-17β-ol benzoate (42723-64-8,73658-36-3) → dl-Δ1-5β-androsten-3-oxo-17β-ol benzoate (1971-67-1,42723-65-9,73658-37-4)

Guidance literature:

With acetic anhydride; t-butyl chromate; acetic acid; In 1,1,2,2-tetrachloroethylene; at 86 - 88 ℃; for 0.75h;

DOI:10.1021/ja00522a060

Reference yield:

benzoyl chloride (98-88-4) → dl-Δ1-5β-androsten-3-oxo-17β-ol benzoate (1971-67-1,42723-65-9,73658-37-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / pyridine / 0.5 h / steam bath

2: 91.1 mg / tert-butyl chromate reagent, glacial AcOH, Ac₂O / tetrachloroethene / 0.75 h / 86 - 88 °C

With pyridine; acetic anhydride; t-butyl chromate; acetic acid; In 1,1,2,2-tetrachloroethylene;

DOI:10.1021/ja00522a060

Reference yield:

dl-Δ1-5β-androsten-17β-ol (894-65-5,42723-63-7,61619-29-2,76978-72-8) → dl-Δ1-5β-androsten-3-oxo-17β-ol benzoate (1971-67-1,42723-65-9,73658-37-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / pyridine / 0.5 h / steam bath

2: 91.1 mg / tert-butyl chromate reagent, glacial AcOH, Ac₂O / tetrachloroethene / 0.75 h / 86 - 88 °C

With pyridine; acetic anhydride; t-butyl chromate; acetic acid; In 1,1,2,2-tetrachloroethylene;

DOI:10.1021/ja00522a060

upstream raw materials:

2α-Brom-17β-benzoyloxy-5α-androstanon-(3)

1-testosterone

benzoyl chloride

stanolone benzoate

Downstream raw materials:

mesterolone

testosterone benzoate

Benzoic acid (5R,8S,9R,10S,13R,14R,17R)-4-bromo-10,13-dimethyl-3-oxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl ester

1α-azidohexyl-3,3-ethylenedioxy-5α-androstane-17β-yl benzoate

Refernces

• 1、 Gravestock, Michael B.,Morton, Douglas R.,Boots, Sharon G.,Johnson, William S.. "Biomimetic Polyene Cyclizations. Participation of the Methylacetylenic Terminator and Nitroalkanes. A Synthesis of Testosterone". . p. 800 - 807. Retrieved 2007/10/02.