Technology Process of C27H33ClN4O3*ClH
There total 8 articles about C27H33ClN4O3*ClH which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C15H22ClN3; 3-(2,3-dimethoxy-phenyl)-isoxazole-5-carbaldehyde;
With
sodium tris(acetoxy)borohydride;
In
dichloromethane;
at 20 ℃;
for 14h;
Molecular sieve;
With
hydrogenchloride;
In
diethyl ether;
Molecular sieve;
DOI:10.5012/bkcs.2012.33.12.4227
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-chloro-succinimide; pyridine / tetrahydrofuran / 0.67 h / 60 °C / Inert atmosphere
1.2: 2 h / 50 °C / Inert atmosphere
2.1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C / Molecular sieve
3.1: sodium tris(acetoxy)borohydride / dichloromethane / 14 h / 20 °C / Molecular sieve
3.2: Molecular sieve
With
pyridine; N-chloro-succinimide; sodium tris(acetoxy)borohydride; pyridinium chlorochromate;
In
tetrahydrofuran; dichloromethane;
DOI:10.5012/bkcs.2012.33.12.4227
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C / Molecular sieve
2.1: sodium tris(acetoxy)borohydride / dichloromethane / 14 h / 20 °C / Molecular sieve
2.2: Molecular sieve
With
sodium tris(acetoxy)borohydride; pyridinium chlorochromate;
In
dichloromethane;
DOI:10.5012/bkcs.2012.33.12.4227
