2,3,5,6-TETRAFLUORO-P-XYLENE

Base Information

• Chemical Name: 2,3,5,6-TETRAFLUORO-P-XYLENE
• CAS No.: 703-87-7
• Molecular Formula: C8H6F4
• Molecular Weight: 178.129
• Hs Code.: 29039990
• Mol file: 703-87-7.mol

Synonyms:1,4-Dimethyltetrafluorobenzene;1,2,4,5-Tetrafluor-3,6-dimethylbenzol;1,2,4,5-Tetrafluoro-3,6-dimethylbenzene;2,3,5,6-Tetrafluoro-1,4-xylene;

Chemical Property of 2,3,5,6-TETRAFLUORO-P-XYLENE

Chemical Property:

• Vapor Pressure: 6.68mmHg at 25°C
• Melting Point: 35-37 °C(lit.)
• Refractive Index: 1.43
• Boiling Point: 143.5 °C at 760 mmHg
• Flash Point: 47.2 °C
• PSA: 0.00000
• Density: 1.283 g/cm³
• LogP: 2.85980
• Storage Temp.: 2-8°C
• Solubility.: slightly sol. in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3,5,6-Tetrafluoro-p-xylene >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5,6-TETRAFLUORO-P-XYLENE

There total 9 articles about 2,3,5,6-TETRAFLUORO-P-XYLENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

Hexafluorobenzene (392-56-3) + methyllithium (917-54-4) → 1,4-dimethyl-2,3,5,6-tetrafluorobenzene (703-87-7)

Guidance literature:

In diethyl ether; for 3h; Heating;

DOI:10.1016/S0022-1139(00)85095-2

Reference yield: 23.0%

1,2,4,5-Tetrafluorobenzene (327-54-8) + methyl iodide (74-88-4) → 2,3,5,6-tetrafluorotoluene (5230-78-4) + 1,4-dimethyl-2,3,5,6-tetrafluorobenzene (703-87-7)

Guidance literature:

With potassium methanolate; In ammonia; at -40 - -33 ℃; for 4h; Title compound not separated from byproducts;

Reference yield:

1,2,4,5-Tetrafluorobenzene (327-54-8) → 2,3,5,6-tetrafluorotoluene (5230-78-4) + 1,4-dimethyl-2,3,5,6-tetrafluorobenzene (703-87-7)

Guidance literature:

With sodium amide;

upstream raw materials:

Hexafluorobenzene

methyllithium

1,2,4,5-Tetrafluorobenzene

methyl iodide

Downstream raw materials:

N¹-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N³,N⁵-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide

N-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)acetamide

N¹-(4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)-N¹-methylpropane-1,3-diamine

(E,E)-1-(4(dibutylamino)styryl)-4-(((3-(1,3-dioxoisoindolin-2-yl)propyl)(methyl)amino)styryl)-2,3,5,6-tetrafluorobenzene

Refernces

• 1、 -. "PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL". Page/Page column 5. . Retrieved 2010/06/19.
• 2、 -. "Method of preparing tetrahalobenzene compounds, chemical intermediates used therein and certain of the compounds themselves". . . Retrieved 2008/06/13.