N-Nitrosomethylamine

Base Information

• Chemical Name: N-Nitrosomethylamine
• CAS No.: 64768-29-2
• Molecular Formula: CH4 N2 O
• Molecular Weight: 60.0556
• UNII: 638YVT1BYD
• DSSTox Substance ID: DTXSID00215076
• Nikkaji Number: J438.786D
• Wikidata: Q27156080
• Mol file: 64768-29-2.mol

Synonyms:N-Nitrosomethylamine;Methylnitrosamine;N-Nitrosomethanamine;Methanamine, N-nitroso-;N-methylnitrous amide;64768-29-2;UNII-638YVT1BYD;638YVT1BYD;Methyldiazohydroxide;MONOMETHYLNITROSAMINE;METHANE DIAZOHYDROXIDE;METHYLAMINE, N-NITROSO-;CHEBI:82565;DTXSID00215076;C19568;C20306;Q27156080

Chemical Property of N-Nitrosomethylamine

Chemical Property:

• Vapor Pressure: 800mmHg at 25°C
• Boiling Point: 23.6°Cat760mmHg
• PKA: -2.78±0.70(Predicted)
• Flash Point: 17.3°C
• PSA: 44.95000
• Density: 1.12g/cm³
• LogP: 0.45760
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 60.032362755
• Heavy Atom Count: 4
• Complexity: 20

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNN=O

Technology Process of N-Nitrosomethylamine

There total 7 articles about N-Nitrosomethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(N-nitrosomethylamino)phenylmethanol (52135-63-4) → methanediazohydroxide (64768-29-2) + benzaldehyde (100-52-7)

Guidance literature:

In water; acetonitrile; at 25 ℃; Rate constant;

DOI:10.1021/ja961178h

Reference yield:

N-methyl-N''-nitro-N-nitrosoguanidine (70-25-7) + Cysteamine (60-23-1) → methanediazohydroxide (64768-29-2) + N-Methyl-N'-nitroguanidine (4245-76-5) + S-nitroso-2-aminoethanethiol (67616-42-6) + C3H8N4O2S

Guidance literature:

With potassium chloride; at 40 ℃; Rate constant;

DOI:10.1021/ja00049a017

Reference yield:

N'-benzoyl-N-methyl-N-nitrosourea (847499-86-9) → N,N'-dibenzoylurea (965-04-8) + (E)-methanediazoate (64768-29-2) + benzamide (55-21-0,27208-38-4) + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; water; at 25 ℃; Further Variations:; pH-values; Reagents; Kinetics;

DOI:10.1002/ejoc.200400537

upstream raw materials:

1-thiopropane

N-methyl-N''-nitro-N-nitrosoguanidine

mercaptoacetic acid

Methyl thioglycolate

Downstream raw materials:

2-hydroxy-5-nitro-benzaldehyde methylhydrazone

Refernces

• 1、 Mesi?, Milan,Revis, Cynthia,Fishbein, James C.. "Effects of structure on the reactivity of α-hydroxydialkylnitrosamines in aqueous solutions". . p. 7412 - 7413. Retrieved 2007/10/03.