Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

Quinacrine hydrochloride

Base Information Edit
  • Chemical Name:Quinacrine hydrochloride
  • CAS No.:69-05-6
  • Molecular Formula:C23H30 Cl N3 O . 2 Cl H
  • Molecular Weight:472.886
  • Hs Code.:
  • European Community (EC) Number:200-700-8,204-989-1
  • NSC Number:757307,14229
  • DSSTox Substance ID:DTXSID40926553
  • NCI Thesaurus Code:C67059
  • ChEMBL ID:CHEMBL556980
  • Mol file:69-05-6.mol
Quinacrine hydrochloride

Synonyms:Acrichine;Atabrine;Atebrin;Dihydrochloride, Quinacrine;Dimesylate, Quinacrine;Hydrochloride, Quinacrine;Mepacrine;Monoacetate, Quinacrine;Monohydrochloride, Quinacrine;Monomesylate, Quinacrine;Quinacrine;Quinacrine Dihydrochloride;Quinacrine Dihydrochloride, Dihydrate;Quinacrine Dihyrochloride, (R)-Isomer;Quinacrine Dihyrochloride, (S)-Isomer;Quinacrine Dimesylate;Quinacrine Hydrochloride;Quinacrine Monoacetate;Quinacrine Monohydrochloride;Quinacrine Monomesylate;Quinacrine, (+-)-Isomer;Quinacrine, (R)-Isomer;Quinacrine, (S)-Isomer

Suppliers and Price of Quinacrine hydrochloride
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Quinacrine dihydrochloride
  • 25g
  • $ 275.00
  • TCI Chemical
  • Quinacrine Dihydrochloride Hydrate
  • 25g
  • $ 106.00
  • Sigma-Aldrich
  • Quinacrine, Dihydrochloride - CAS 69-05-6 - Calbiochem A non-specific phospholipase A2 (PLA2) inhibitor.
  • 100mg
  • $ 53.46
  • Sigma-Aldrich
  • Quinacrine dihydrochloride ≥90%
  • 25 g
  • $ 121.00
  • Sigma-Aldrich
  • Quinacrine dihydrochloride ≥90%
  • 100 g
  • $ 396.00
  • Medical Isotopes, Inc.
  • QuinacrineDiHCl
  • 500 mg
  • $ 2000.00
  • DC Chemicals
  • Quinacrine dihydrochloride >98%
  • 1 g
  • $ 98.00
  • DC Chemicals
  • Quinacrine dihydrochloride >98%
  • 500 mg
  • $ 64.00
  • CSNpharm
  • Mepacrine2HCl
  • 100mg
  • $ 54.00
  • CSNpharm
  • Mepacrine2HCl
  • 25mg
  • $ 35.00
Total 31 raw suppliers
Chemical Property of Quinacrine hydrochloride Edit
Chemical Property:
  • Appearance/Colour:yellow crystals or powder 
  • Melting Point:ca. 248 - 250 C (decomposes) 
  • Refractive Index:1.6300 (estimate) 
  • PKA:pKa -6.3(H2O t undefined I not reported but low) (Uncertain) 
  • PSA:37.39000 
  • Density:1.2962 (rough estimate) 
  • LogP:6.84740 
  • Storage Temp.:+15C to +30C 
  • Solubility.:DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly) 
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:9
  • Exact Mass:435.1844180
  • Heavy Atom Count:29
  • Complexity:461
Purity/Quality:

98%,99%, *data from raw suppliers

Quinacrine dihydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s): Xn 
  • Hazard Codes:Xn 
  • Statements: 22-36/37/38 
  • Safety Statements: 36/37/39 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC.Cl
  • Uses A non-specific PLA2 inhibitor. and acetylcholine receptor antagonist Quinacrine is a derivative of acridine that is chemically and clinically very similar to 4-aminoquinolines. It was the primary drug for prevention and therapy of malaria during World War II. Today it is rarely used for treating malaria, although it is used to treat amebiasis. Synonyms of this drug are mepacrine, atabrine, acrisuxin, and others. In treating resistant forms of malaria, tetracycline is also used in combination with pyrimethamine, sulfonamides, sulfones, and dapsone, which is widely used for treating leprosy (as a rule, in combination with pyrimethamine). Quinacrine dihydrochloride has been used:in its uptake and accumulation studies in mouse lung slices using fluorescence microscopein the staining of ATP vesicles in mesenchymal stem cells (MSCs)in uptake-release assay for characterization of dense granule functionality of platelets
  • Indications Quinacrine is no longer used extensively as an antimalarial drug and has been largely replaced by the 4- aminoquinolines.
  • Clinical Use Giardiasis Prophylaxis of malaria Tapeworm infections
Post RFQ for Price